Saratov JOURNAL of Medical and Scientific Research

rheumatic diseases

Rheumatology profile patients adherence to treatment with non-steroidal anti-inflammatory drugs

Year: 2020, volume 16 Issue: №1 Pages: 99-103
Heading: Sociology of Medicine Article type: Original article
Authors: Smotrova Yu.N., Novokreshchenova I.G., Akulova A.I.
Organization: Saratov State Medical University
Summary:

The aim of the study is to assess the degree of adherence of patients with rheumatic diseases to the treatment of non-steroidal anti-inflammatory drugs (NSAIDs). Material and Methods. 196 patients were surveyed using a specially designed questionnaire, which included Morisky — Green test. Statistical data processing was carried out by methods nonparametric statistics (criterion x2)- Results. Patients took NSAIDs in rheumatoid arthritis (50.0%), ankylosing spon-dylitis (37.8%), vertebrogenic dorsalgia (20.4%). 49.0% of patients took NSAIDs constantly, 39.3% — during courses of treatment, 11.7% — on demand (in pain). 81.1 % of patients were engaged in self-treatment of NSAIDs. 20 patients (10.2%) were adherent to the treatment of NSAIDs, 29 patients (14.8%) were insufficiently adherent (patients were united in one group), 147 patients (75.0%) were not adherent to the treatment. Non-adherent patients mostly violated the regimen of treatment if they felt well (85.7%). For adherent patients the most significant motive was deterioration after taking NSAID (20.4%). Adherent patients mostly had higher education in relation to non-adherent (71.4 and 53.7% respectively) (x2=6.647; p<0.05). Side effects of NSAIDs were absent in 73.5% of adherent patients and in 32,0% of non-adherent (x2=24.795; p<0.01). Conclusion. The level of education, the frequency of side effects and subjective assessment of the patient's state of health affect the degree of adherence of patients with rheumatic diseases to the treatment of NSAIDs.

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Occurrence and features of uveitis in patients with rheumatic diseases: current peculiarities of clinical examination and patient management.

Year: 2017, volume 13 Issue: №2 Pages: 358-361
Heading: Ophtalmology Article type: Original article
Authors: Dzhalavyan Y.V., Kamenskikh T.G., Gamayunova K.A., Gaydukova I.Z.
Organization: Saratov State Medical University
Summary:

The objectives of the study are to establish the occurrence of uveitis in patients with rheumatic diseases, to assess the features of the uveitis in rheumatic disease in children and adults, and to analyze the effectiveness of theirtreatment. Materials and Methods. The study included 670 people with RH (stage I) and 35 patients who had uveitis and / or rheumatic fever who agreed to undergo additional ophthalmologic bleeding (stage II), including a standard ophthalmological examination including visiometry, biomicroscopy of the anterior segment, ophthalmoscopy of the posterior segment of the eye, refractometry, optical coherence tomography in angiomode(tomograph-angiograph CIRRUS HD-OCT MODEL 5000 (Carl Zeiss, Germany), dopplerography of the vessels of the eye. Results. The prevalence of uveitis in rheumatic diseases was established in 21%, which is higher than that in the general population. Uveitis in rheumatic diseases is recurrent and well-treated condition with frequent and complete improvement of visual acuity, and angiographycal features of uveitis, p <0,05 for all parameters. Conclusions. The high incidence of uveitis and relapsing their course in rheumatic diseases lead to necessity of an ophthalmologist's examination every 6 months. It is desirable to perform a comprehensive angiographic examination of uvea for the timely detection of erased and subclinical forms of uveitis.

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