Saratov JOURNAL of Medical and Scientific Research

Fomkina O.A.

Saratov State Medical University, Department of Anatomy, Assistant, Candidate of Medical Science

Morphometric parameters of cerebral arteries in the elderly

Year: 2019, volume 15 Issue: №1 Pages: 94-97
Heading: Human anatomy Article type: Original article
Authors: Fomkina О.А., Gladilin Yu.A.
Organization: Saratov State Medical University
Summary:

Objective: to identify the features of morphometric parameters of cerebral arteries in adults aged 55-74 years. Material and Methods. As a material of the study we used samples of anterior (АСА), middle (MCA), posterior cerebral (PCA), posterior connective (PCoA), basilar arteries (BA) and vertebral arteries (VA), seized at autopsy 21 corpses of adults who died in old age. External diameter, wall thickness and length of arteries were studied by morphometry. The lumen diameter was calculated as the difference between the outer diameter and the doubled wall thickness. The material was processed by variational-statistical method. Results. The article presents the average values and parameters of variability of the main morphometric parameters of arteries supplying the brain. The results of the comparative analysis with the average values typical for adults aged 21-90 years are presented. Conclusion. The length, wall thickness, outer diameter and lumen diameter of the cerebral arteries in adults 55-74 years are characterized by significant variability. In the studied age range, АСА and PCA are characterized by the same wall thickness; MCA and VAare the same wall thickness, outer diameter and lumen diameter. The wall thickness of BA and VA in the elderly is 28.1 and 17.9% higher than the average value typical for people 21-90 years.

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Anatomy of the posterior communicating artery

Year: 2018, volume 14 Issue: №1 Pages: 25-29
Heading: Human anatomy Article type: Review
Authors: Fomkina О.А., Nikolenko V.N., Gladilin Yu.A.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

Purpose: to generalize and systematize the information available in the literature about the anatomy of the posterior connective arteries in adults. Scientific works (monographs, articles, dissertations and abstracts of dissertations) of native and foreign authors for the period from 1928 to 2017 were worked out to achieve the goal. Data on the variants of artery discharge, areas of blood supply and major anomalies are presented. The size characteristics of arteries (length, outer diameter, wall thickness and lumen diameter) are presented taking into account bilateral, age and sexual differences.

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The influence of premorbid background on the course of urolithiasis

Year: 2017, volume 13 Issue: №2 Pages: 280-283
Heading: Urology Article type: Original article
Authors: Osnovin O.V., Popkov V.M., Fomkina O.A.
Organization: Saratov State Medical University
Summary:

Aim: to analyze the correlation between the unfavorable factors at newborn patients and children and the peculiarities of the course of urolithiasis in adults. Material and Methods. The data were received from questioning of 286 patients and their relatives, analysis of case histories and past medical histories. The material was statistically worked out. Results. The early development of urolithiasis (at patients under 30) was associated with the threat of termination of pregnancy, prematurity, excretory and digestive disorders at childhood in case of severe anamnesis of urolithiasis, and also malnutrition. Bilateral lesions of the urinary system were determined to be associated with artificial feeding and prematurity, digestive diseases and complicated anamnesis of urolithiasis, malnutrition, deprived living conditions and low income. Stones in calyces occurred at patients with different complications at birth. More frequent cases of stone formation in renal pelvis were observed at premature and malnutrition patients and patients with cardiovascular diseases occurred during the childhood. Stones in ureters were considered as a result of respiratory diseases effect. Conclusion. Unfavorable factors occurred at birth and childhood, factors concerned with deprived social conditions and psychological problems influence the onset and the course of urolithiasis.

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То the anniversary of Vladimir Nikolaevich Nikolenko

Year: 2016, volume 12 Issue: №4 Pages: 622-624
Heading: anniversary Article type: Short message
Authors: Aleshkina O.Yu., Fomkina О.А.
Organization: Saratov State Medical University
Summary:

The article is devoted the 60th anniversary of the honored worker of higher school of the Russian Federation, professor Vladimir Nikolaevich Nikolenko.

Biomechanical modelling of cerebral arteries at different variants of configuration of intracranial arteries of vertebrobasilar system

Year: 2016, volume 12 Issue: №2 Pages: 118-127
Heading: Macro- and Micromorphology Article type: Original article
Authors: Fomkina О.А., Ivanov D.V., Kirillova I.V., Nikolenko V.N.
Organization: Saratov State Medical University, Saratov state university
Summary:

The purpose is to consider the biomechanical modelling of cerebral arteries at different structural variants of intracranial arteries of vertebrobasilar system. Material and methods. By means of the system of the final and element analysis ANSYS on the basis of data on geometry, morphometricand biomechanical properties of cerebral arteries their biomechanical models have been constructed. On the received models for 9 structural variants of intracranial arteries of vertebrobasilar system, haemodynamic parameters and parameters of the intense deformed condition of walls of arteries have been analyzed. Results. The most frequent variant of a configuration of intracranial department of vertebrobasilar system is the combination of average in size of angles of connection of vertebrata and bifurcation of basilar arteries. Such option occurs in 49% of cases. More rare variant (1,5% of cases) with the narrow angles of connection of vertebrata and bifurcations of basilar arteries has been observed. The design of intracranial arteries of vertebrabasi-lar system exerts an impact on distribution of bloodflow and effective tension in a vascular wall of back brain arteries. Conclusion. According to the study it has been determined that the constructed individual biomechanical models may provide information on some parameters of haemodynamics and the intense deformed condition of a vascular wall which causes the development of atherosclerosis and intracranial aneurisms.

Anatomy of sphenoid part of middle cerebral artery in adults

Year: 2016, volume 12 Issue: №1 Pages: 15-18
Heading: Macro- and Micromorphology Article type: Review
Authors: Fomkina О.А., Nikolenko V.N., Gladilin Yu.A.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The information about anatomy of middle cerebral artery in adults has been summarized on the basis of data analysis of domestic and foreign scientific literature. Material concerning options for arteries discharge, area of blood supply, major anomalies and size characteristics (outer diameter, wall thickness, lumen diameter) has been represented in this work.

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Training of doctors at the department of normal anatomy of the Saratov university during World War I.

Year: 2015, volume 11 Issue: №3 Pages: 354-359
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Aleshkina O.Yu., Gladilin Yu.A., Fomkina O.A.
Organization: Saratov State Medical University
Summary:

The article presents the data concerning the organization of department of Normal Human Anatomy at the Saratov University and its work during the period from 1909 to 1916.

Keywords: -
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The interrelation between length parameters of the proximal phalanges and the middle and distal phalanges of the 2-5th fingers

Year: 2015, volume 11 Issue: №3 Pages: 247-249
Heading: Macro- and Micromorphology Article type: Short message
Authors: Bikbaeva T.S., Aleshkina O.Yu., Nikolenko V.N. Fomkina O.A.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

Objective: to determine the volume and direction of correlations of length of the proximal phalanges of the 2-5th fingers of the hand with osteometric parameters of phalanges of like fingers. Material and Methods. The length of proximal, medium and distal phalanges, as well as the width and height: the bases, body and heads (distal tuberosity) phalanges of fingers of the hand were studied on 150 skeletons of adult men and women hands at the age 21-90 years old. Results. The correlation between the length of proximal phalanges and pulse- high-rise parameters of proximal, medium and distal phalanges of 2-5th fingers of hand was determined. Conclusion. The length of the proximal phalange forms a different strength and direction of the correlation. The lengths of the proximal phalanges have a positive direction of moderate strength with all parameters of middle phalanges and the average degree of correlation with the length of the distal phalanges, the width of its base and the body.

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Anatomy of the precommunication part of the anterior cerebral artery in adults

Year: 2014, volume 10 Issue: №4 Pages: 607-611
Heading: Macro- and Micromorphology Article type: Review
Authors: Fomkina О.А., Nikolenko V.N., Gladilin Yu.A.
Organization: Saratov State Medical University
Summary:

Based on the data analysis of foreign and native literature information about the anatomy of the anterior cerebral artery in adults has been summarized. The data on options for arteries discharge, the area of blood supply, major anomalies and the magnitude of its size characteristics (outer diameter, wall thickness, lumen diameter) have been considered in the work under the study.

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Anterior cerebral artery variants according to individually-typological and combined variabilities of its morphological and biomechanical features

Year: 2013, volume 9 Issue: №1 Pages: 28-33
Heading: Macro- and Micromorphology Article type: Original article
Authors: Fomkina О.A., Nikolenko V.N.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The purpose of the article is to define variants of anterior cerebral artery (АСА) of adults depending on typological and combined variability of its morphological and biomechanical features. Material and methods: The research has included 228 samples of anterior cerebral arteries, 115 corpses of people aged 21-84 years received on autopsy. The following points have been under the research: external and internal diameters, wall thickness, general strength, strength range, absolute and relative deformation of an artery. Results: According to the studied parameters 3 groups of variants of arteries have been allocated: with average size of a sign (M±s), with lesser size of a sign ( M + s). Combined variability of morphological and biomechanical features of АСА has been presented. Conclusion: АСА groups with higher variability, especially at men, have been observed in 2,2-2,6 times more often, than at women. As exception, thin-walled АСА which in 1,7 times more often taped at women have been considered. It has been revealed that subjects of alternative group III in 1,2-1,7 times older than those of alternative group I of arteries. Age of subjects who have been classified according to biomechanical parameters of АСА wall has been approximately identical (r=0,28-0,51). The experimentally received data about morphological, deforming and strengthening features may be of great value in studying of blood flow modeling and in optimization of intravascular interventions on cerebral arteries.

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