Saratov JOURNAL of Medical and Scientific Research

Eremin A.V.

I. M. Sechenov First Moscow State Medical University, Vice-rector for Public Relations and Educational Work, PhD

Prognostic factors in clinical management of root resorption (review)

Year: 2020, volume 16 Issue: №2 Pages: 474-477
Heading: Stomatology Article type: Review
Authors: Savina Е.А., Eremin A.V., Eremin O.V.
Organization: Saratov State Medical University
Summary:

A literature review is devoted to root resorption of a permanent tooth. Literature data, eLibrary Internet resources and PubMed National Library of Medicine databases databases for 2010-2020 (34 sources) were used to collect the research material. Timely diagnosis using cone beam computed tomography, which provides visualization in the three-dimensional space of root resorption, allows a conservative adequate endodontic intervention and improves the medical effectiveness of the treatment.

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Assessment of cardiovascular risk factors in patients with chronic peri-odontitis

Year: 2020, volume 16 Issue: №1 Pages: 45-49
Heading: Stomatology Article type: Original article
Authors: Eremin A.V., Lipatova Т.Е., Lepilin A.V., Eremin V.I.
Organization: Saratov State Medical University
Summary:

Aim: to estimate the cardiovascular risk in patients with chronic periodontitis (CP) different severity. Material and Methods. 2400 persons (65.6% male, aged from 40 to 64 years) were examined. Body mass index, lipid spectrum, blood glucose and C-reactive protein levels were determined, and tonometry was performed. The 10-year risk of a cardiovascular event was calculated using SCORE (Systematic Coronary Risk Evaluation) and Reynolds Risk Score. The concentration of interleukin-6 (IL-6) in the oral fluid was studied. Results. Patients with moderate to severe CP are characterized a high incidence of the main cardiovascular risk factors (arterial hypertension, smoking, dyslipidemia, obesity) compared to those with person with intact periodontal tissue and patients with mild CP For patients with CP with a moderate risk of fatal cardiovascular events on the SCORE, it is advisable to calculate the cardiovascular risk on the Reynolds Risk Score too. The oral fluid's level of IL-6 in the patients with CP may be considered as an additional marker of high risk of fatal cardiovascular events. Conclusion. The relation between the results of severe CP as missing teeth, loss of periodontal bone and the risk of fatal cardiovascular events is important for clinical use and may be used as an additional cardiovascular risk marker for patients with chronic periodontitis.

Keywords: -
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Features of dental prosthetics at patients with chronic periodontitis and coronary heart disease

Year: 2019, volume 15 Issue: №2 Pages: 251-256
Heading: Stomatology Article type: Original article
Authors: Lepilin A.V., Eremin A.V., Lipatova T.E.
Organization: I.M. Sechenov First Moscow State Medical University, Saratov State Medical University
Summary:

Objective: at patients with chronic generalized periodontitis in combination with chronic ischemic heart disease to study the change of cytokines, biomarkers of osteoproliferation and osteoresorption in comparison with the character- istics of endothelial functions and the determine rational approaches to prosthetics. Material and Methods. 90 patients with periodontitis and coronary heart disease, who use metal, metal-ceramic and removable partial dentures using thermoplastic resin were survey. We studied of cytokines, markers of bone metabolism in the oral fuid, evaluated va-sodilating, vasoconstrictor and adhesive endothelial function. Results. The coronary heart disease in combination with chronic periodontitis is characterized by the endothelial dysfunction, which associated with the activity of periodontitis. Biochemical manifestations of periodontitis, bone resorption and endothelial dysfunction are more pronounced by the use patients metal dentures compared to metal-ceramic and removable partial dentures using thermoplastic resin. Conclusion. The use of patients at periodontitis and coronary heart disease metal dentures, in contrast to patients using metal-ceramic and removable partial dentures using thermoplastic resin, is accompanied the increase of biochemical markers of infammation and bone resorption in the oral fuid and the endothelial dysfunction.

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Features of dental prosthetics at patients with chronic periodontitis and coronary heart disease

Year: 2019, volume 15 Issue: №2 Pages: 251-256
Heading: Stomatology Article type: Original article
Authors: Lepilin A.V., Eremin A.V., Lipatova T.E.
Organization: I.M. Sechenov First Moscow State Medical University, Saratov State Medical University
Summary:

Objective: at patients with chronic generalized periodontitis in combination with chronic ischemic heart disease to study the change of cytokines, biomarkers of osteoproliferation and osteoresorption in comparison with the character- istics of endothelial functions and the determine rational approaches to prosthetics. Material and Methods. 90 patients with periodontitis and coronary heart disease, who use metal, metal-ceramic and removable partial dentures using thermoplastic resin were survey. We studied of cytokines, markers of bone metabolism in the oral fuid, evaluated va-sodilating, vasoconstrictor and adhesive endothelial function. Results. The coronary heart disease in combination with chronic periodontitis is characterized by the endothelial dysfunction, which associated with the activity of periodontitis. Biochemical manifestations of periodontitis, bone resorption and endothelial dysfunction are more pronounced by the use patients metal dentures compared to metal-ceramic and removable partial dentures using thermoplastic resin. Conclusion. The use of patients at periodontitis and coronary heart disease metal dentures, in contrast to patients using metal-ceramic and removable partial dentures using thermoplastic resin, is accompanied the increase of biochemical markers of infammation and bone resorption in the oral fuid and the endothelial dysfunction.

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Periodontal disease at cardiovascular pathology

Year: 2019, volume 15 Issue: №2 Pages: 246-251
Heading: Stomatology Article type: Review
Authors: Eremin A.V., Lepilin A.V., Lipatova T.E.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The purpose of the systematic literature review was to characterize existing problem of the relationship between cardiovascular diseases and periodontal diseases on the basis of information analysis of the Russian and English original studies and metanalyses published in open access bibliographical databases such as eLibrary and PubMed the past ten years as a methodological basis for future clinical and experimental studies

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Regenerative capabilities of the skin

Year: 2018, volume 14 Issue: №4 Pages: 738-739
Heading: Dermatovenerology Article type: Author's opinion
Authors: Eremina M.G., Eremin A.V., Eldesbaeva Ya.S., Drozdova S.B., Roshchepkina E.M., Chumachenko Yu.V.
Organization: Saratov State Medical University
Summary:

The skin is the largest organ of the human body and has many functions. Stem cells of the epidermis and hair follicles are necessary for homeostasis and skin regeneration, which leads to the restoration of the integrity and function of the damaged tissue. Currently, we are actively searching for the best therapeutic strategies to restore the barrier function of the skin. Stem cells are recognized as potential candidates for the treatment of numerous skin pathologies. Therapeutic strategies of modern medicine require an understanding of the potential uses of stem cells for treating skin diseases.

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Purpose and methods of teaching dermatovenereology to students of the medical university

Year: 2017, volume 13 Issue: №3 Pages: 686-688
Heading: Dermatovenerology Article type: Short message
Authors: Utz S.R., Slesarenko N.A., Eremina M.G., Eremin A.V., Utz I.A.
Organization: Saratov State Medical University
Summary:

 Higher education is based on the assimilation of theoretical knowledge acquired in the process of teaching, practical skills and the development of intellectual abilities leading to self-development and creative thinking. The ultimate goal of education is the education of the student's need for cognitive activity, the result of which will be competence in the profession, the ability to think in the terms of the dermatovenereology subject materials and the khowledge of it.

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Clinical case of a Goldenhar syndrome diagnostics in a newborn boy

Year: 2016, volume 12 Issue: №3 Pages: 511-513
Heading: Dermatovenerology Article type: Case report
Authors: Slesarenko N.A., Eremina M.G., Belonogova Y.V., Roshepkin V.V., Eremin A.V.
Organization: Saratov State Medical University
Summary:

Relative importance of the current issue is based on rare occurrence of this dermatosis, its genetic predisposition and occurrence in early childhood. The Goldenhar syndrome diagnosing is a difficult task and causes difficulty in selecting treatment, due to large number of clinical syndromes presenting with facial deformities and the inability to quickly identify concomitant signs of damage to other organs and systems.

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