Saratov JOURNAL of Medical and Scientific Research

Khvorostukhina N.F.

Saratov State Medical University, Department of Obstetrics and Gynaecology of Therapeutic Faculty, Assistant Professor, Candidate of Medical Science

Analysis of Effectiveness and Safety of Assisted Delivery

Year: 2014, volume 10 Issue: №2 Pages: 346-349
Heading: Proceedings of all-Russia week of science with international participants Article type: Original article
Authors: Kozlova T.U., Khvorostukhina N.F., Novichkov D.A., Bebeshko O.I.
Organization: Saratov State Medical University
Summary:

Aim: to study the outcomes of labour after the application of «KIWI» vacuum-system. Materials and Methods. Retrospective analysis of labour records with vacuum-extraction of fetus (main group: n=35) and with emergency cesarean section (comparison group: n=18)on indications similar to those in the main group, has been undertaken. Results. High rate of extragenital pathology in groups (70,7% and 72,3%) as well as aggravated obstetric-gynecologic anamnesis (36,9% and 55,6%) has been revealed. Pregnancies of 50,7% women of the main group have been complicated by placentofetal insufficiency and chronic fetal hypoxia; in the comparison group 27,7% threatened miscarriage has been observed accordingly in 20% and 33,3%. Conditions for vacuum extraction have been the following: fetus asphyxia (52,3%), labour pains weakness (47,7%). Having evaluated the state of health of the new-born children of the main groupstraight complications (cephalohematomas, cervical injury, subaponeurotic hemorrhage, Duchen-Erb paresis, intraventricularhemorrage) have been observed in 53,8% of children. In the comparison group direct complications have been marked in 22,3% of cases. Conclusions. Comparatively high rate of labour traumatism in the main group may be explained by violations in conditions and techniques of vacuum-extractions as well as by non-observance of indications and contra-indications for the application of this operational method during the labour of pregnant women of high risk groups.

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Risk factors of intestinal obstruction in pregnancy

Year: 2012, volume 8 Issue: №3 Pages: 723-728
Heading: Obstetrics and Gynecology Article type: Original article
Authors: Khvorostukhina N.F., Salov I.A., Rogozhina I.E., Stolyarova U.V.
Organization: Saratov State Medical University
Summary:

Objective: to study risk factors and options for clinical course of acute intestinal obstruction in pregnancy. Materials and methods. A detailed study of history, clinical course, diagnosis and treatment characteristics of acute intestinal obstruction in 79 pregnant women was undertaken. Results: It was determined that a combination of intestinal obstruction, and pregnancy is more common for II and III trimester of gestation (88,5%), with more likely to develop mechanical obstruction caused by the adhesive process (77,2%). Risk factors for intestinal obstruction in pregnancy are: chronic diseases of gastrointestinal tract, surgery of abdominal cavity and pelvis, burdened obstetric and gynecological history and long-term use of progestogens during pregnancy. Difficulties in diagnosis are associated with absence of classical symptoms of disease that is caused by changes in topographical relations of abdominal cavity, increasing size of uterus, as well as lack of immune response to the emergence of a pathological process. Conclusion. Formation of pregnant women at risk for development of intestinal obstruction and preventive measures to address violations of intestinal motor function can reduce the risk of disease. Algorithm of medical tactics for suspected acute intestinal obstruction in pregnancy, allowing to reduce time of diagnosis and provision of medical care.

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Lowinvasive technologies and hemostasis system at a hysteromyoma

Year: 2011, volume 7 Issue: №3 Pages: 587-592
Heading: Obstetrics and Gynecology Article type: Original article
Authors: Rogozhina I.E., Khvorostukhina N.F.
Organization: Saratov State Medical University
Summary:

Research objective. Study of condition of hemostasis system at patients with hysteromyoma complicated by bleeding; comparative estimation of hemostasis indicators at patients with uterine arteries embolization (the basic group n=48) and abdominal hysterectomy (comparison group n=65). Materials and methods. Complex study of the basic hemogram parameters and hemostasis at 162 patients with hysteromyoma and 30 patients without marked genital pathology (the II control group) was carried out. 48 patients formed the main group which was subjected to uterine arteries embolization for bleeding break; 65 patients (the comparative group) were surgically operated upon abdominal hysterectomy; 49 patients with hysteromyoma had no bleedings and formed the control group. Research of hemostasis system was carried out by means of test-tube method, and also by plotting set for express-diagnostics, analysis of thrombocyte unit of hemostasis system was realized with 2-channel analyzer of thrombocyte aggregation «Biola» — LA 230. Results. Presented analysis of hemostasiogram parameters allows to state development of chronic DIC-syndrome in women with hysteromyoma. Reliable shortening of coagulation index, decrease of thrombocyte aggregation function in comparison to the control group data were revealed. Conclusion. Development of hyper coagulation with increase of paracoagulative products with simultaneous activation of fibrinolysis processes in all the patients with hysteromyoma was revealed. Minimal effect of embolization of uterine arteries to hemostasis system in patients with hysteromyoma was marked. And they were intensified after surgical treatment, which is the evidence of definite advantages of this method unlike of hysterectomy

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ON THE OCCASION OF THE 135 YEARS OF THE BIRTH OF THE FIRST SARATOV PROFESSOR OBSTETRICIAN-GYNECOLOGIST NIKOLAY M. KAKUSHKIN

Year: 2008, volume 4 Issue: №3 Pages: 142-144
Heading: History of Medicine. Anniversary Dates Article type: Short message
Authors: I.A. Salov, N.F. Khvorostukhina, T.I. Turlupova, K.M. Karagezyan
Organization: Saratov State Medical University
Summary:

The article represents the main milestones ofN.M. Kakushkin’s biography- outstanding obstetrician-gynecologist, the first head of department of obstetrics and gynecology in Saratov State Medical University; italso reflects his life conditions and scientific activity, that had formed his world view as a talented scientist and clinician.

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