Saratov JOURNAL of Medical and Scientific Research

Gavrilova E.S.

South Ural State Medical University, Department of Polyclinic Therapy and Clinical Pharmacology, Assistant

The clinical significance of palivi-zumab in the prevention of severe respiratory infections in newborn infants

Year: 2016, volume 12 Issue: №2 Pages: 165-167
Heading: Pediatrics Article type: Case report
Authors: Bykova Е.М., Gavrilova E.S., Borisova А.А., Pazgalyova N.V., Panina O.S., Chernenkov Yu.V.
Organization: Saratov State Medical University
Summary:

Palivizumab is known as the world's first drug with proven efficacy for passive immunization of severe infections of lower respiratory tract in preterm infants. The paper describes a clinical case of application of palivizumab (sinagis) at a newborn infant with bronchopulmonary dysplasia complicated by episodes of obstructive bronchitis. Particular attention is paid to the mechanism of action of palivizumab on the respiratory syncytial virus providing the data on a clinical picture of respiratory syncytial virus infection in a premature baby and showing the effectiveness of the drug in infants.

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Clinical case of the course of congenital alveolar-capillary dysplasia of the lungs at a newborn

Year: 2016, volume 12 Issue: №2 Pages: 162-164
Heading: Pediatrics Article type: Case report
Authors: Gavrilova E.S., Borisova А.А., Bykova Е.М., Pozgalyova N.V., Panina O.S., Chernenkov Yu.V.
Organization: Saratov State Medical University
Summary:

The article describes a clinical case of a child with an alveolar-capillary dysplasia of the lungs — a rare cause of pulmonary hypertension at a newborn. This pathology is of particular interest from a clinical point of view as it rarely occurs in the clinical practice of a neonatologist. It should be noted that the prenatal diagnosis of this disease is of significant difficulty. The authors found it necessary to highlight the cause of development, the clinical presentation and the methods of diagnostics of alveolar-capillary dysplasia of the lungs.

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Prognostic significance of delirium in the intensive care period of acute myocardial infarction

Year: 2016, volume 12 Issue: №1 Pages: 36-39
Heading: Anaesthesiology and Reanimatology Article type: Original article
Authors: Yulin A.S., Ermakov M.A., Gavrilova E.S., Astakhov A.A.
Organization: South Ural State Medical University
Summary:

The aim: to identify the frequency and clinical features of delirium in acute myocardial infarction (AMI) in the conditions of the intensive care unit. Material and Methods. The study involved 104 patients (43,3% women and 56,7% men) with AMI during the stay at the intensive care unit. The average age was 68,0 [59,0-76,7] years. Delirium was diagnosed using the criteria questionnaire Moss-ICU. For neurodevelopmental testing we used screening tests and rating scales. Results. The incidence of delirium in patients in this category was 28,8%. Most frequently delirium develops in patients aged 60-89 years: in the age group 60-74 years 25,0%, in the group of 75-89 years 44,7%. Delirium developed in the 1-2 day stay in the intensive care unit and intensive care. The average duration of delirium was 7,7 days. Hypoproductive form of delirium was detected in 64,3% of all cases, hyperproductive form in 21,4% of patients, mixed form in 14,2% of patients. The occurrence of delirium is associated with an increase of the duration of stay at the intensive care unit at 6 times compared with patients without delirium. Conclusion. The presence of delirium greatly increases the probability of death in the reanimation period of acute myocardial infarction. Moss questionnaire and training of doctors to work with rating scales should be accepted in all ICU intensive care units for early diagnosis of delirium and immediate correction of disorders of consciousness in patients in critical condition.

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