Saratov JOURNAL of Medical and Scientific Research

fertilization in vitro (IVF)

Aggressive posterior retinopathy of prematurity in a child conceived by in vitro fertilization

Year: 2018, volume 14 Issue: №4 Pages: 882-885
Heading: Ophtalmology Article type: Case report
Authors: Latypova E.A., Somova A.B., Matryuk D.I., Abdrakhmanova Yu.A.
Organization: Bashkir State Medical University of the Russian Health Care, «Republican Children's Clinical Hospital», Ufa
Summary:

Aggressive posterior retinopathy of prematurity (AP-ROP) is the most severe form ofretinopathy of prematurity (RP), characterized by early onset, fulminant course with absence of stagingand resistance to treatment. Today, the increase in AP-ROPincidence is associated with the changing standards for nursingof severely premature infants and wideprevalence of assisted reproductive technology — in vitro fertilization (IVF). The article presents a clinical case of aggressiveposterior retinopathy of prematurity in a girl with agestational ageof 25 weeks and a birth weightof about 860 grams who was conceived by IVF. Medical and high-tech laser treatment, fullycarried out in time, has lead toregression of this disease, which mayallowto preserve and develop visual function.

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Premature infants' health at multiple induced pregnancy.

Year: 2015, volume 11 Issue: №3 Pages: 305-309
Heading: Pediatrics Article type: Original article
Authors: Chernenkov Yu.V., Nechaev V.N., Stasova Yu.V., Tereshenko V.A.
Organization: Saratov State Medical University
Summary:

Objective: to define the risk factors adversely influencing prenatal development at premature birth at use of methods of assisted reproductive technology (ART); to estimate premature' infants health from multiple induced pregnancy according to Perinatal Center of Saratov for last 3 years. Material and Methods. Under supervision there were 139 pregnant women with application ART. 202 children (51 twins were born and 5 triplet babies), from them 83 premature infants born from multiple induced pregnancy have been analyzed. Results. The newborns examined by method ART, were distributed as follows: 22-28 weeks — 19 children; 29-32 weeks — 23; 33-36 weeks — 41. Asphyxia at birth was marked at all premature infants. Respiratory insufficiency at birth is revealed in 87,3% of cases. The most frequent pathologies in premature infants are revealed: neurologic infringements and bronchopulmonary pathology occured at all children, developmental anomaly — 33, 8%, retinopathies in premature infants — 26,5%. The mortality causes include: extreme immaturity, cerebral leukomalacia, IVN 3 degrees. Conclusion. The risk factors, premature birth at application of methods ART are revealed: aged primiparas, pharmacological influence, absence of physiological conditions of prenatal development; multifetation. The high percent of birth of children with ELBW and ULBW is revealed. RDCN with further BPD development, retinopathies in premature infants and CNS defeat is more often occured.

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