Saratov JOURNAL of Medical and Scientific Research

Sholomov I.I.

Saratov State Medical University, Head of Department of Nervous System Diseases, Professor, Doctor of Medical Science

Types of cephalalgia syndrome observed in medical students of Saratov State Medical University

Year: 2019, volume 15 Issue: №1 Pages: 177-179
Heading: Neurology Article type: Original article
Authors: Salina Е.А., Parsamyan R.R., Kuznetsova Е.В., Sholomov I.I., Uzhakhov A.M., Shichanina E.K.
Organization: Saratov State Medical University
Summary:

Purpose: to study the prevalence and clinical features of headache among medical students. Material and Methods. 160 students from the medical faculty on their 3rd and 6th years of education were surveyed. The type of headache was determined according to the International Classification of Headache (version 3, 2018). Neuropsychological status of students with tension headaches was studied with use of Schulte test, digital character substitution test, hospital anxiety and depression scale (HADS), test for determining sleepiness and sleep quality, tests for semantic and phonetic activity and memory. Statistical analysis was performed using MS Excel 2010 Results. The most common type of headache among medical students was primary headache, namely tension headache (78.2%). Migraine without aura (20.5%) and cluster headache (1.3%) were less common. Changes in the neuropsychological status were revealed in students suffering from tension headache. Conclusion. A study conducted among medical students showed a high prevalence of primary headache with a predominance of tension headache combined with anxiety and sleep disorders.

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Effectiveness criteria of early rehabilitative treatment of patients with postoperative upper plexopathy

Year: 2017, volume 13 Issue: №1 Pages: 057-061
Heading: Neurology Article type: Original article
Authors: Tosheva M.l., Sholomov I.I., Sholomova E.l.
Organization: Saratov State Medical University
Summary:

The damage of the peripheral nervous system often acts as a complication of extensive surgical interventions on the removal of malignant breast tumors. The research goal is to evaluate the criteria for the effectiveness of early rehabilitation treatment of postoperative upper plexopathies. Material and Methods. The analyzed results of complex diagnosis and treatment of 162 women undergoing radical mastectomy for breast cancer, aged 33 to 79 years were presented. The examination included neurological examination, analysis of the psychological state using the HADS scales, Janet Taylor and HDRS, holding electroneuromyography Results. 98.76% of cases of patients after radical mastectomy for malignant breast tumors were diagnosed with unilateral shoulder complex. At 1.24% it established a bilateral lesion of the brachial plexus. The presence of pain is not a leading complaint in all cases. Among patients with classical mastectomy performed significantly prevailed damage of the intercostal nerves III and IV. In post-operative patients with the retrofit radical mastectomy neuro- and plexopathy were often diagnosed. Consent to one-stage reconstructive surgery is directly correlated with the level of education and marital status. Indicators of depression and anxiety were lower after reconstructive plastic surgery. Conclusion. The criteria for the effectiveness of early rehabilitation treatment of postoperative upper plexopathies were obtained. The decisions on the nature and scope of reconstructive and plastic surgery were established to be in conjunction with the social components of life of patients.

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Comorbid diseases at patients with HIV-induced neurological disorders

Year: 2016, volume 12 Issue: №3 Pages: 388-390
Heading: Neurology Article type: Original article
Authors: Sholomova E.l., Rebrov К.А., Sholomov I.I.
Organization: Saratov City clinic №11, Saratov State Medical University
Summary:

Objective: to estimate the structure and frequency of detection of secondary diseases in patients with neurological manifestations of HIV infection. Materials and methods. The study involved 304 patients infected with HIV. Results. The defeat of the nervous system in HIV infection occur encephalopathy, cerebral vascular lesions, meningitis, subacute encephalitis, secondary CNS lesions. The number of CD4-lymphocytes in HIV-infected patients with neurological disorders was significantly lower. Most of them have comorbid diseases. The most commonly diagnosed hepatitis С and B, herpes, cytomegalovirus infection, chlamydia, Candida, toxoplasmosis and tuberculosis, mixed infection. Hepatitis В and С and herpes are the most widely represented in patients with HIV-induced encephalopathy and cerebrovascular form of HIV. The presence of cytomegalovirus infection is correlated with the development of subacute encephalitis. Conclusion. Manifestations of nervous system pathology in HIV polymorphic and correlated with the presence of secondary comorbid pathology. Such conditions are due to underlying disease immunological parameters.

Neuron specific enolase as a marker of the nervous system damage in primary hypothyroidism

Year: 2016, volume 12 Issue: №2 Pages: 264-267
Heading: Neurology Article type: Original article
Authors: Kuznetsova Е.В., Gerasimov S.V., Sholomov I.I.
Organization: Saratov Regional Clinical Hospital, Saratov State Medical University
Summary:

In order to predict and detect neurological complications at somatic diseases earlier, there have recently been started to use some of the markers determined in the patient's blood serum. Aim of the study. The aim of the work was to evaluate the activity of neuron specific enolase (NSE) in patients with primary hypothyroidism (PHT). Materials and methods. In 110 patients with PHT detailed study of neurological and neuropsychological status, determined NSE level in serum. Results. The results of this study showed that the NSE activity depended on the gender, age of the patient, the duration of existence of the endocrinopathy and the presence / absence of neurological symptoms. Conclusion. Produced a comprehensive assessment of the state of the nervous system in patients with PHT, NSE defined value as a non-specific marker NA lesions in these patients. The goal set at the beginning of the study, achieved.

Personal peculiarities in patients with middle cerebral artery infarction

Year: 2013, volume 9 Issue: №4 Pages: 695-697
Heading: Neurology Article type: Original article
Authors: Antonova N.A., Sholomov I.I.
Organization: Saratov State Medical University
Summary:

The purpose of the work is to reveal personal peculiarities in patients who have suffered middle cerebral artery infarction. Material and Methods. 39 patients with middle cerebral artery infarction have been under the study. All patients have received clinical instrumental inspection (neurologic survey, duplex ultrasound investigation of vessels of neck, head and brain, the research CT or MRT). Personal peculiarities have been studied by "The standard multiple-factor method of research of the personality" (PITCHES). Results. Psychological reactions for the disease have been determined. They include hypochondria, depression, psychasthenia and anxiety. Conclusion. Personal peculiarities in patients suffered from middle cerebral artery infarction may be characterized by the appearance of psychological response to the psychotraumatic situation. Therefore it is necessary to give psychotherapeutic aid.

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The study of a balance function using video stabilom-etry in patients with ataxia

Year: 2013, volume 9 Issue: №1 Pages: 92-97
Heading: Otolaryngology Article type: Original article
Authors: Mareev О.V., Sholomov I.I., Gorozhankin А. V., Monakhova O.A.
Organization: Engels Technological Institute of Saratov State Technical University n.a. Yu.A. Gagarin
Summary:

The aim of the study is to assess the condition of balance function in patients with different diseases. Materials and methods: The study has been performed on 82 patients divided into the following groups: patients with Menier»s disease, with multiple sclerosis, chronic cerebral ischemia, and persons without pathology of balance function, which have composed the comparison group. Statistical evaluation of video stabilometric data of patients in these groups has been performed. Results: Reliable differences between stabilometric parameters in patients with disorder of balance function and patients of comparison group have been revealed. Conclusion: Video stabilometry may be applied as an objective method for evaluation of balance function in order to detect different pathological states.

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Spectral analysis of slowly wave activity in able to work patients with cognitive-mnestic deficiency

Year: 2012, volume 8 Issue: №3 Pages: 775-777
Heading: Neurology Article type: Author's opinion
Authors: Ganovich Е.А., Zhestikova M.G., Simenikhin В.A., Sholomov I.I., Makluchenko U.A., Rikhtor T.N.
Organization: Saratov State Medical University, Novokuznetsk Post-graduate Medical Institute, Myski Rehabilitation Centre «Topaz», Kemerovo State Medical University
Summary:

The problem of dementia in the modern medicine has been becoming one of the most actual nowadays. In the foundation of cognitive-mnestic dysfunction in the structure of vibration disease there is a biological action of industrial vibration on the central nervous system as well as on the whole body. The analysis of literature provides data on insufficient study of cognitive-mnestic aspect in the structure of vibration disease and also interaction with affective and anxious sphere in people working in the conditions of vibration impact.

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Neurological complications in primary hypothyroidism and possibility of their correction

Year: 2012, volume 8 Issue: №2 Pages: 560-563
Heading: Neurology Article type:
Authors: Sholomov I.I., Lutoshkina E.B., Gerasimov S.V., Salina E.A.
Organization: Saratov State Medical University, Regional Hospital
Summary:

Aim of the study. The authors assessed the state of the nervous system in patients with primary hypothyroidism before and after the treatment. Materials and methods. In 115 patients studied in detail the neurological and neuro-psychological status, to assess the status of the peripheral nervous system was performed electroneuromyography. Results. These results indicate that obligate the defeat of the nervous system in primary hypothyroidism, for the correction of which can be successfully used by neurotrophic agents. Conclusion. The study assessed the condition of the nervous system in patients with primary hypothyroidism before and after the treatment. The goal set at the beginning of the study, has been achieved.

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Subclinical forms of neuropathy with diaphyseal fractures of the humerus

Year: 2012, volume 8 Issue: №2 Pages: 556-560
Heading: Neurology Article type: Original article
Authors: Sholomova E.I., Romanenko V.Yu., Ninel V.G., Аrutyunyan Т.R., Sholomov I.I., Shuldyakov А.А.
Organization: Saratov Scientific Research Institute of Traumatology and Orthopedics, Saratov State Medical University
Summary:

Aim of the study. To identify the frequency of subclinical neuropathy in patients with diaphyseal fractures of the hu-merus in different periods of treatment. Materials and methods. Held clinical-following systems survey of 122 patients with diaphyseal fractures of the shoulder bone. Results. At 57 after neurological examination and electromyographic diagnosed with post-traumatic neuropathy. Conclusion. As a result of research implemented its purpose. Revealed the frequency of post-traumatic neuropathy, as complications of fractures of the shoulder bone. Not always the defeat of the peripheral nerves of the manifest clinically, which complicates the diagnosis. Give a description of the locations and forms of damage, describes in detail the dynamics of the violations identifed in the course of treatment. Considered are the questions of diagnostics of latent forms of neuropathy and stages of their manifestations.

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Divergence of clinical features and neuroimaging results in stroke-provoked aphasia

Year: 2006, volume 2 Issue: №2 Pages: 552-556
Heading: Neurology Article type: Original article
Authors: Sholomov I.I., Ornatskaya N.A., Mescheryakova Y.B.
Organization: Saratov State Medical University, State Military Hospital (Saratov — 63)
Summary:

Aim of the study. Aim of the study. Materials and methods. Clinical and neuroimaging survey of 58 patients with acute stroke and aphasia is conducted. For identifcation aphasia type it agrees the classifcation of A. R. Lury accepted in our country, speech functions were investigated by E. D. Homsky’s technique. Results. By comparison of results of neuropsychological and neuroimaging researches it is revealed that in 40 % of cases localization of the lesion doesn’t correspond to the diagnosed type of aphasia. In group of clinical features and neuroimaging results divergences existence of average correlation communication between severity of aphasia and age of patients, and also severity of aphasia and the general weight of neurologic manifestations of a stroke is revealed. Indicators of expressiveness of neurologic defciency and speech violations in this group were authentically below, than in group of compliance. Conclusion. In 40 % of cases localization of the lesion doesn’t correspond to the diagnosed type of aphasia. Topic discrepancy appears in atypical cortical (21,74 %) and subcortical (47,83 %), location and also in tomographic lesion absence (30,43 %).

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