Saratov JOURNAL of Medical and Scientific Research

Optimization of complex treatment of aggressive peri-odontitis using immunocorrecting therapy

Year: 2011, volume 7 Issue: №2 Pages: 485-490
Heading: Stomatology Article type: Original article
Authors: Vedyaeva A.P., Bulkina N.V., Smirnov D.A., Zakharova N.B.
Organization: Saratov State Medical University
Summary:

Application of immunomodulatorGepon in treatment of aggressive periodontitis provides the normalization of cyto-kine balance of periodontal pockets exudate by raising the level of anti-inflammatory cytokines (IL-1(3, IL-8, IFN-y) and osteoprotegerin, indirectly confirming the improvement of bones of alveolar processes of jaws, as well as by significant decrease in the concentration of proinflammatory cytokines (IL-4, IL-10) and transforming growth factor (3. Gepon application improves the efficiency of preoperative period, accelerates postoperative rehabilitation of patients and helps achieve remission period up to 6 months in 71 % of cases, which is in 28% higher than in patients receiving traditional treatment

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