Saratov JOURNAL of Medical and Scientific Research

Choroid thickness dependending on the anteroposterior eyeball size and age in healthy persons

Year: 2020, volume 16 Issue: №2 Pages: 575-578
Heading: Ophtalmology Article type: Original article
Authors: Balalin A.S., Khzardzhan Yu.Yu., Fokin V.P., Balalin S.V., Sarkisyan A.S.
Organization: S. Fyodorov Eye Microsurgery Federal State Institution

The purpose of the study is to define the dependence of choroid thickness (CT) from age and anteroposterior eyeball size (APES) in healthy persons. Material and Methods. We analysed data on 62 patients (62 eyes) aged 25 to 78 without retina and/or optic nerve pathology (45.5±1.7, M±m). Anteroposterior size of the eyeball was from 21.39 to 28.75 mm (23.97±0.18 mm, M±m). The examination included determination of the best corrected visual acuity, optical coherence tomography and optic biometry. Choroidal thickness was measured on two B-scans (vertical and horizontal) in the projection of the fovea and at 24 points from the fovea (in the superior, inferior, nasal and temporal sections) with an interval of 500 urn from each other. Results. CT is predominantly thinner peripapillary and in the inferior section of retina (p<0.01). CT is inversely proportional to the anteroposterior eyeball size (p<0.01). Calculation formula and a chart map of normal values of the choroid thickness depending on APES are proposed. Dependence on age was statistically unreliable (p=0.68). Conclusion. A method for calculating individual values of the choroidal thickness depending on the anteroposterior eyeball size is proposed. This method can be applied in practice in the diagnosis of pachychoroid diseases.

1. Linsenmeier RA, Padnick-Silver L. Metabolic Dependence of Photoreceptors on the Choroid in the Normal and Detached Retina. Investigative Ophthalmology & Visual Science 2000 Sept; (41): 3117-3123.
2. Spector R, Keep RF, Snodgrass RS, et al. A balanced view of choroid plexus structure and function: Focus on adult humans, Experimental Neurology 2015; (267): 78-86.
3. Nickla DL, Wallman J. The multifunctional choroid. Prog Retin Eye Res 2010; (29): 144-68.
4. Wei WB, Xu L, Jonas JB, Shao L, et al. Subfoveal choroidal thickness: the Beijing Eye Study. Ophthalmology 2013 Jan; 120 (1): 175-80.
5. Shin JW, Shin YU, Cho HY, et al. Measurement of Choroidal Thickness in Normal Eyes Using 3D OCT-1000 Spectral Domain Optical Coherence Tomography. Korean J Ophthalmol 2012 Aug; 26 (4): 255-9.
6. Entezari M, Karimi S, Ramezani A, et al. Choroidal Thickness in Healthy Subjects. J Ophthalmic Vis Res 2018 Jan-Mar; 13(1): 39-43.
7. Tarutta EP, Markosyan GA, Sianosyan AA, Milash SV. The thickness of the choroid in various types of refraction and its dynamics after sclerotherapy. Russian Ophthalmological Journal 2017; 10 (4): 48-53.
8. Belekhova SG, Astakhov YuS. Comparative analysis of morphometric parameters of the retina and optic nerve disc obtained on various types of optical coherent tomographs. Ophthalmological Statements 2018; (4): 45-50.
9. Tan CS, Ouyang Y, Ruiz H, Sadda SR. Diurnal Variation of Choroidal Thickness in Normal, Healthy Subjects Measured by Spectral Domain Optical Coherence Tomography. Invest. Ophthalmol Vis Sci 2012; 53 (1): 261-6.
10. Astakhov YuS, Belekhova SG, Dal NYu. The thickness of the choroid is normal and with age-related macular degeneration. Ophthalmological Statements 2014; (1): 4-7.
11. Doga AV, Pedanova YeK ОСТ signs of pachychoroid neovasculopathy. Modern Technologies in Ophthalmology 2020; (1): 303-5.
12. Volodin PL, Klepinina OB, Pedanova YeK. Changes in the retinal structure with pachychoroid pigmented epithelial disease. Modern Technologies in Ophthalmology 2019; (1): 251-4.
13. Pedanova YeK, DogaAV, Kachalina GF, etal. OCT-EDI in the diagnosis and the effectiveness evaluation of pachychoroidal neovascularization treatment. Modern Technologies in Ophthalmology 2016; 1: 175.
14. Stoyukhina AS, Budzinskaya MV, Stoyukhin SG, Aslamazova AE. Optical coherence tomography-angiography in ophthalmic oncology. The Russian Annals of Ophthalmology 2019; 135 (1): 104-11.

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