Saratov JOURNAL of Medical and Scientific Research

Oxidative stress and methods of its correction in corneal burns (review)

Year: 2020, volume 16 Issue: №2 Pages: 459-463
Heading: Ophtalmology Article type: Review
Authors: Kolesnikov A.V., Kirsanova I.V., Sokolova A.I., Ban E.M.
Organization: Ryazan State Medical University n.a. I.L.Pavlov

The article presents actual ideas about the role of oxidative stress in the pathogenesis of corneal burns and methods of its correction. Corneal burns are rather common ophthalmic pathology. Corneal burns are difficult to treat, so they often lead to a decrease in visual acuity and, as a result, disability of young people. Despite the high antioxidant protection of the eye structures, under the influence of damaging environmental factors on the cornea (ultraviolet, chemicals, high temperatures, etc.), there is an increase in the concentration of free radicals with a decrease in the level of antioxidants — oxidative stress develops, aggravating damage to the cornea. Medicaments with antioxidant properties have shown their efficacy in the treatment of corneal burns.

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