Saratov JOURNAL of Medical and Scientific Research

Prospects for the use of terahertz therapy in dental implantation in conditions of chronic tobacco intoxication (an experimental study)

Year: 2020, volume 16 Issue: №1 Pages: 39-44
Heading: Stomatology Article type: Original article
Authors: Bulkina N.V., Makarova N.I., Ivanov P.V., Nikishin D.V.
Organization: Penza State University, Saratov State Medical University, «Aptos»
Summary:

Objective: to determine the features of peri-implant tissues healing in conditions of tobacco intoxication and the possibility of their correction by using electromagnetic terahertz radiation at the frequency (EMR THF) of 129.0 GHz. Material and Methods. 36 rabbits were divided into control group and three experimental ones. In the experimental groups, tobacco intoxication was simulated for 6 weeks, then implantation was performed and tobacco intoxication was maintained until the end of the experiment. In the 1st experimental group, physiotherapy was not performed; in the 2nd and 3rd groups, various schemes of THF therapy were used. The results were evaluated using histological methods. Results. In the control group, the most active regeneration processes were noted. Among the experimental groups, the best indicators were achieved in the groups where THF radiation was used. The thickness of the connective tissue layer after 1 month was significantly lower in the 2nd and 3rd groups, amounting to 48.0±3.9 and 42.7±3.4 urn, respectively, than in the 1st group: 76.4±3.5 urn (p<0.05), this dynamics continued after 3 months. Osteogenesis in the 2nd and 3rd groups took place with less cartilage formation than in the 1st group (p<0.05). Conclusion. Analysis of histomorphom-etry data shows the effectiveness of THF therapy for the correction of the regeneration process violations after dental implantation in conditions of tobacco intoxication.

Bibliography:
1. WHO: Report on the Global Tobacco Epidemic, 2019. Geneva: World Health Organization, 2019.
2. Safyanova NV, Chukhlovin AB, Shaporova NL, et al. The possibility of creating an experimental model to study the effects of smoking on the pi-, p2-adrenergic receptors, M-cholinergic receptors of blood vessels and bronchi. Regional blood circulation and microcirculation 2013; 12 (2): 64-73.
3. Soldatova YuO, Bulgakova Al, Gantseva HH, Khismatullina FR. Investigation of the effect of smoking on oral health indicators and the relationship amount of carbon monoxide from smoking experience. Periodontology 2016; 21 (1): 26-9.
4. AL-Bashaireh AM, Haddad LG, Weaver M, et al. The effect of tobacco smoking on musculoskeletal health: a systematic review. Journal of Environmental and Public Health 2018; 018: 4184190.
5. Silin AV, Nekhoroshev AS, Danilova NB, et al. Modern view on dental status in smokers according to preventive medicine. Preventive and clinical medicine 2018; 1 (66): 5-10.
6. Takamiya AS, Goiato МС, Gennari FH. Effect of smoking on the survival of dental implants. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014; 158 (4): 650-3.
7. Mumcu E, Beklen A. The effect of smoking on the marginal bone loss around implant-supported prostheses. Tobacco Induced Diseases 2019; 17: 43.
8. Ivanov PV, Makarova Nl, Bulkina NV, Zyulkina LA. Modern views on the osseointegration of dental implants (literature review). University proceedings: Volga region: Medical sciences 2018; 4 (48): 191-202.
9. Yen CY, Tu YK, Ma CH, et al. Measurement of tibial endothelial cell function after cigarette smoking, cessation of smoking and hyperbaric oxygen therapy. Injury 2008; Suppl 4: 40-6.
10. Bulkina NV, Zyulkina LA, Ivanov PV, Vedyaeva AP Experimental validation of application of new xenogenic biomaterials for reconstructive dental procedures in conditions of chronic inflammation. Periodontology 2017; 3 (84): 69-72.
11. Zelenova AV, Bulkina NV, Olenko ES, Tokmakova EV The effectiveness of electromagnetic terahertz radiation use in the treatment of patients with rapidly progressive periodontitis. Saratov Journal of Medical Scientific Research 2015; 11 (4): 556-561.
12. Zyulkina LA. Strategy of planning reconstructive dental interventions in various functional states of the oral microcirculation system: DSc diss. Saratov, 2018; 282 p.

AttachmentSize
2020_01_039-044.pdf845.54 KB

No votes yet