Saratov JOURNAL of Medical and Scientific Research

Retina and optic nerve characteristics in fellow eyes of patients with epiretinal fibrosis after retinal detachment

Year: 2020, volume 16 Issue: №1 Pages: 318-321
Heading: Ophtalmology Article type: Original article
Authors: Yablokov M.M., Nenasheva Yu.V.
Organization: S. Fyodorov Eye Microsurgery Federal State Institution

The purpose of the study was to examine the relation between the state of macular area and optic disc in fellow eyes of patients after rhegmatogenous retinal detachment (RRD) and the development of epiretinal fibrosis in association with silicone tamponade. Material and Methods. The study included 18 patients operated on for RRD using vitreous cavity tamponade by silicone oil. The examination was performed by means of optical coherence tomography-angiography for fellow eyes of patients. Results. Analysis of retinal thickness and volume revealed that the indices were lower in the group with epiretinal fibrosis. When assessing relative vascular density, area and perimeter of foveal avascular zone (FAZ) the indices were prevailed in the group with epiretinal fibrosis. Conclusion. The study revealed a significant decrease in retinal thickness in the fovea of fellow eyes in patients with epiretinal macular fibrosis. A statistically significant decrease in the thickness of the reticular membranes is revealed in patients with epiretinal macular fibrosis. A statistically significant enlargement of the area and an increase in the perimeter of FAZ, an increase in the relative vascular density in the foveal and deep plexuses in the fellow eyes of patients with epiretinal macular fibrosis were revealed as well.

1. Mitry D, Charteris DG, Fleck BW, et al. The epidemiology of rhegmatogenous retinal detachment: geographical variation and clinical assosiations. Br J Ophthalmol 2010; 94 (6): 678-84.
2. Ho JD, Liou SW, Tsai CY, et al. Trends and outcomes of treatment for primary rhegmatogenous retinal detachment: a 9-year nationwide population-based study. Eye 2009; 23 (3): 669-75.
3. Schwartz SD, Flynn HW. Pars plana vitrectomy for primary rhegmatogenous retinal detachment. Clin Ophthalmol 2008; 2(1): 57-63.
4. Khudyakov AYu, Zhigulin AV. Regarding vitrectomy in treating non-complicated rhegmatogenous retinal detachment. In: Modern technologies in the treatment of vitreoretinal pathology — 2010: Collected papers. Moscow, 2010; p. 176-8.
5. Takhchidi KhP. Endovitreal surgery — reality of the times. In: IX Congress of ophthalmologists of Russia: abstracts. Moscow, 2010; 232-3.
6. Riemann CD, Miller DM, Foster RE. Outcomes of transconjunctival sutureless 25-gauge vitrectomy with silicone oil infusion. Retina 2007; 27 (3): 296-303.
7. Shah CP, Ho AC, Regillo С D. Short-term outcomes of 25-gauge vitrectomy with silicone oil for repair of complicated retinal detachment. Retina 2008; 28 (5): 723-8.
8. Nam KY, Kum JY Effect of internal limiting membrane peeling on the development of epiretinal membrane after pars plana vitrectomy for primary rhegmatogenous retinal detachment. Retina 2015; 35 (5): 880-5.
9. Katira RC, Zamani M, et al. Incidence and characteristics of macular pucker formation after primary retinal detachment repair by pars plana vitrectomy alone. Retina 2008; 28 (5): 744-8.
10. Macbemer R. Proliferative vitreoretinopathy — a personal account of its pathogenesis and treatment. Invest Ophthalmol 1988; 29: 1771-83.
11. Sella R, SternfeldA, etal. Epiretinal membrane following pars plana vitrectomy for rhegmatogenous retinal detachment repair. Int J Ophthalmol 2019; 12 (2): 1872-77.
12. Lyskin PV, Zakharov VD, Zgoba Ml. Change in the concentration of inflammation markers after intraoperative endolaser coagulation performed during surgery of retinal detachment. Practical medicine 2017; 110 (9): 166-70.
13.Wickham LJ, Asarid RH, et al. Immunopathology of intraocular silicone oil: retina and epiretinal membranes. Br J Ophthalmol 2007; 91 (2): 258-62.
14. Tanoka Y, Toyoda F, et al. Clinicopathological features of epiretinal membranes in eyes filled with silicone oil. Clin Ophthalmol 2018; 12: 1947-57.
15. Sdobnikova SV, Mazurina NK, Stolyarenko GE. Modern approach to the treatment of proliferative diabetic retinopathy. Russian Medical Journal 2002; 3 (3): 99-105.
16. Tankovskiy VE, Mizerova OV. Vasoproliferation in retinal vein thrombosis. Proliferative syndrome in ophthalmology. International scientific and practical conference: Collected papers. Moscow, 2000; 20-21.
17. Errera М.Н., Liyanage S.E., Elgohary М, et al. Using spectral-domain optical coherence tomography imaging to identify the presence of retinal silicone oil emulsification after silicone oil tamponade. Retina 2013; 33 (8): 1567-73. DOI: 10.1097/IAE. 0b013e318287d9ea.

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