Saratov JOURNAL of Medical and Scientific Research

Terahertz therapy at frequencies of the molecular spectrum of nitric oxide: results and prospects of clinical use

Year: 2019, volume 15 Issue: №3 Pages: 800-806
Heading: Cardiology Article type: Original article
Authors: Parshina S.S., Afanasyeva T.N., Vodolagin A.V., Petrova V.D., Ushakov V.Yu., Kaplanova T.l., Potapova M.V., Ramazanova Z.G.
Organization: Saratov State Medical University, Clinical Hospital "RZD-Medicine", Saratov

The purpose of the study is to summarize the results of clinical use of terahertz therapy at molecular spectrum of nitric oxide frequencies (150,176... 150,664 GHz) (THZ-therapy-NO) in cardiology, to identify general regularities and peculiarities of terahertz therapy influence. Material and Methods. We examined 312 patients with angina pectoris (150 patients with unstable angina pectoris, and 162 patients with stable angina of III-IV f. to.). Results. Antianginal effect of THZ-therapy-NO does not depend on the form of angina, sex, age, mode of exposure, hypocoagulation effect of smoking. We identified 2 types of effects of THZ-therapy-NO on hemostasis and blood rheology: active antithrombotic and protective (prevents the development of hypercoagulation shifts against the standard drug treatment). Procoagulant hemostasis is most sensitive to terahertz exposure. Reducing the duration of course exposure leads to expansion of antithrombotic effect by increasing the activity of natural anticoagulants (antithrombin III). Conclusion. Antianginal effect of THZ-therapy-NO does not depend on its hypocoagulation action. Irradiation mode "3/15" is optimal for patients with angina. Mode "2/5" does not have its own antithrombotic effect, therefore it is suitable for patients with angina with a tendency to hypocoagulation. Smoking does not affect the efficiency of the THZ-therapy-NO.

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