№2, 2019, volume 15

The purpose of the systematic literature review was to characterize existing problem of the relationship between cardiovascular diseases and periodontal diseases on the basis of information analysis of the Russian and English original studies and metanalyses published in open access bibliographical databases such as eLibrary and PubMed the past ten years as a methodological basis for future clinical and experimental studies

Objective: to study the clinical and neurological features in patients with chronic cerebral ischemia, depending on the presence of venous cerebral dysfunction. Material and Methods. 168 patients sufering from chronic cerebral ischemia took part in the study (mean age 61.2±3.8 yrs; 45.2 % — men). The control group comprised 20 healthy subjects comparable in age and sex distribution. All patients with chronic cerebral ischemia underwent rheoencephalographya for detection of cerebral venous dysfunction, as well as standard clinical and neurological examination (patient»s complaints, past history, neurological status assessment). Clinical features of headache were evaluated using the original questionnaire. The intensity of headache were determined using a ten-point visual-analog scale. Cognitive function was assessed in all study groups by means of evoked potential method with using P300 technique. Results. In patients with chronic cerebral ischemia in 46.4 % of cases revealed venous cerebral symptoms. In such patients, headache syndrome is most pronounced, both by clinical criteria and by visual-analog scale score: 6.8 points against 5.1 points in patients with chronic cerebral ischemia without venous cerebral dysfunction (p<0.05). In patients with chronic cerebral ischemia with concomitant cerebral palsy revealed more pronounced comorbid background and cognitive defcits, manifested in violation of sensory integration, diferentiation of stimuli, memory and decision-making as compared with patients with chronic cerebral ischemia without venous cerebral dysfunction and healthy subjects. Conclusion. Venous cerebral dysfunction aggravated the course of chronic brain ischemia predominantly due to the presence of cognitive defciency.

At the heart of the development of twin-to-twin transfusion syndrome (TTTS) is the presence of pathological anastomoses in the placental vascular network. The article presents a clinical case of TTTS development in monochorionic twins with placental vessel abnormality with a diagnostic search and a plan of further management.

The research goal is to study of blood lipid profile for different types of feeding in infants with low birth weight (LBW), very low birth weight (VLBW) and extremely low birth weight (ELBW) at birth, receiving breast milk or special mixes, to determine whether correction of their food. Material and Methods. The dynamic study of cholesterol (CS), triglycerides (TG), high-density lipoproteins (HDL) and low-density lipoproteins (LDL) was carried out depending on the type of feeding in low-weight infants of different weight categories. The concentration of these lipid components was determined using the test of Liquick Cor-CHOL; Liquick Cor-TG; CORMAY HDL DIRECT systems. Results. This study showed that newborns with extremely low birth weight with intrauterine growth retardation and newborns with very low birth weight had significantly lower levels of lipid profile than infants with low birth weight (CS — by 11-17%, TG — by 18-27%, HDL — by 33-47%, LDL— by 14%). Conclusion. Extremely low birth weight newborns with intrauterine growth retardation (IGR) and very low birth weight newborns need early correction of lipid metabolism throughout the neonatal period.

The review is devoted to the choice of the optimal treatment regimen of eradication therapy in children. Main tasks in the treatment of children with gastroduodenal pathology associated with Helicobacter pylori are eradication of the pathogen, restoration of the damaged mucosa and prevention of recurrence of the infection. A particular importance in the composition of eradication schemes is the choice of antibacterial drugs. The main requirements for anti-Helico-bacter therapy regimens used in pediatric practice are: eradication rate of at least 80 %, economic accessibility, good tolerability with minimal severity of adverse reactions, optimal frequency of admission. An analysis of a number of domestic and foreign studies has shown that insufcient adherence of the patient to therapy, the presence of antibacterial resistance, pathogenicity factors in a number of strains of H. pylori have a negative efect on the efectiveness of treatment and should also be taken into account when choosing therapeutic tactics. Successful eradication of H. pylori in most cases depends on the optimal treatment regimen also has an impact on the result.

The article presents the clinical case of patient with chronic thromboembolic pulmonary hypertension. It is describes the classical course of the disease with use of full spectrum of diagnostic procedures. Pulmonary endarterectomy (PEA) is a gold standard of treatment. Nevertheless, performance of PEA is possible in only 60 % of patients with chronic thromboembolic pulmonary hypertension. Balloon pulmonary angioplasty and drug therapy with a stimulator of soluble guanylate cyclase are alternative treatment strategy.

The duration and quality of life of patients undergoing extracorporeal renal replacement therapy are largely dependent on concomitant diseases and conditions. Cardiovascular disease is a significant complication of chronic kidney disease and a major cause of death in patients undergoing hemodialysis. Cardiovascular remodeling is an independent predictor of the risk of cardiovascular events in patients with chronic kidney disease (CKD), including those in the dialysis stage. This paper analyzes the literature on left ventricular myocardial remodeling in the late predialysis stages of CKD and in patients receiving treatment with chronic hemodialysis.