Saratov JOURNAL of Medical and Scientific Research

Informativeness of optical coherence tomography in differential diagnosis of central chorioretinitis and age-related macular degeneration

Year: 2019, volume 15 Issue: №2 Pages: 524-528
Heading: Ophtalmology Article type: Original article
Authors: Popova L.I., Kudryavtseva Yu.V., Demakova L.V., Obsekova K.S.
Organization: Kirov State Medical University
Summary:

Purpose: the analysis of the informativeness of optical coherence tomography as an additional method in the diferential diagnosis of central chorioretinitis and age-related macular degeneration. Material and Methods. Studies conducted in 44 patients. The frst group included 20 patients with central chorioretinitis. The second group consisted of 24 patients with diferent forms of age-related macular degeneration. The informativeness of optical coherence tomography was analyzed in the diferential diagnosis of central chorioretinitis and AMD. Results. Uncomplicated forms of AMD and central chorioretinitis have a diferent tomographic picture. Using the OCT method it is possible to judge the change in the thickness of the choroid which increases in the acute phase of chorioretinitis. In the atrophic form of AMD, the thinning of the choroid extends over a considerable distance. OCT provides additional information on the localization of the infammatory focus. Conclusion. OCT-diferences were found at the level of the pigment epithelium, retinal photoreceptors and choroid in infammatory processes and degenerative diseases, which can help in difcult cases of diferential diagnosis. However, secondary choroidal neovascularization does not have specifc OCT signs in various diseases, since it is a complication of the main process.

Bibliography:
1 Bykovskaya TN. The value of immunological factors in the pathogenesis of bilateral and unilateral uveitis: PhD abstract. Moscow, 2000; 27 p.
2 Penkov MA, Avrushchenko NM, Solomatin II. Complications of peripheral uveitis. Ophthalmol magazine 1987; (3): 156–7
3 Age Related Macular Degeneration: Priority eye diseases / WHO / World Health Organization. [Last accessed on 2011 Feb 6]. URL: http://www.who.int / blindness / causes / priority / en / index8. html
4 Age-related macular degeneration / American Academy of Ophthalmology; Expert Council on Age-Related Macular Degeneration; Interregional Association of Ophthalmologists. St. Petersburg: Publishing House NL, 2009; 84 p.
5 Neroev VV. Russian observational epidemiological non-interventional study of patients with a wet form of age- related macular degeneration. Russian Ophthalmological Journal 2011; 4 (2): 4–9
6 Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 Lancet 2012; 380: 2163–96. DOI: 10.1016 / s0140–6736 (12) 61729–2
7 Schmidt-Erfurth U, Chong V, Loewenstein A, et al. Guidelines for the management of neovascular age-related macular degeneration by the European Society of Retina Specialists (EURETINA). Br J Ophthalmol 2014; 98 (9): 1144– 167 DOI: 10.1136 / bjophthalmol-2014–305702
8 Tonkikh NA. Choroidal neovascularization of various genesis: clinical and immunological characteristics, state of regional hemodynamics: PhD abstract. Chelyabinsk, 2004
9 Panova IE, Avdeeva ON, Varnavskaya NG, Prokopyeva MYu. Spectral optical coherence tomography in evaluating the activity of chorioretinitis of various etiologies. In: Neroev VV, ed. Proceedings of the scientifc-practical conference with international participation […]. Moscow, 2010; vol. 2, p. 206–10.

AttachmentSize
2019_02-1_524-528.pdf2.13 MB

No votes yet