Saratov JOURNAL of Medical and Scientific Research

The use of autologous conditioned platelet rich plasma in the surgery of rhegmatogenous retinal detachment with central, paracentral and peripheral tears

Year: 2019, volume 15 Issue: №2 Pages: 422-425
Heading: Ophtalmology Article type: Original article
Authors: Arsyutov D.G.
Organization: Republican Clinical Ophthalmologic Hospital, Сhuvashia
Summary:

Purpose: to evaluate the efectiveness of surgical treatment of rhegmatogenous retinal detachment with central, paracentral and peripheral tears using autologous conditioned platelet rich plasma (ACP), without endolaser photoco- agulation and silicone oil tamponade. Material and Methods. The operative technique consists of carrying out 25 & 27 Ga vitrectomy, removing the posterior hyaloid membrane, the inner limiting membrane in the presence of a macular hole, pneumoretinopexy. ACP, devoid of leukocytes and containing 1.5–3 times more platelets that found in whole blood is then instilled into the central, paracentral and / or peripheral retinal tears in 2–3 layers including retina around the tear. 59 patients with visual acuity from the correct visual projection to 0.9 were treated. Results. The retina was reattached in 96.6 % of patients and the retinal tears were blocked; two patients with multiple peripheral tears underwent operation. Over a 1–12 months follow up period, 4 recurrent retinal detachments were recorded, which also required repeat surgery. In 93.2 % of patients complete retinal reattachment and blocking of the retinal defect was achieved. The visual acuity of the operated patients was 0.03–0.9. Conclusion. 25 & 27 Ga vitrectomy of retinal detachment with central, paracentral and peripheral tears and blocking of retinal defects with ACP without endolaser photocoagulation of the retina and silicone tamponade is a method that enables total retinal reattachment and better functioning of the operated eye to be achieved in most cases.

Bibliography:
1 Shkvorchenko DO, Zakharov VD, Kakunina SA, et al. Current approaches to rhegmatogenous retinal detachment surgery. Cataract and refractive surgery 2015; 15 (2): 4–10
2 Charles S, Calzada J, Wood B. Vitreous Microsurgery. Moscow: MEDpress-inform, 2012; 400 p.
3 Lyskin PV, Zakharov VD, Zgoba MI. Infuence of endolaser photocoagulation on the postoperative period in patients with retinal detachment. Modern technology in ophthalmology 2017; 1 (14): 173–6
4 Pashtaev NP, Arsyutov DG. Use of medical adhesives in the surgery of progressive myopia and retinal detachment. Ophthalmic surgery 2009; 3: 16–20
5 Achkasov EE, Bezuglov EhN, Ulyanov AA, et al. Application platelet-rich plasma in clinical practice. Biomedicine 2013; 4: 46–59
6 Arsyutov DG. Surgery of rhegmatogenous retinal detachment with the use of platelet-rich plasma (PRP). Practical medicine 2018; 3 (114): 11–3
7 Shkvorchenko DO, Zakharov VD, Shpak AA, et al. Our experience with platelet-rich blood plasma in macular hole surgery. Modern technology in ophthalmology 2016; 1 (9): 245– 6
8 Noskov SM, Shirokova LYu. Application of autologous blood medicines in osteoarthrosis of knee joints. Scientifc and practical rheumatology 2011; 4: 72–4.

AttachmentSize
2019_02-1_422-425.pdf274.85 KB

No votes yet