Saratov JOURNAL of Medical and Scientific Research

Possibility of frameless biopsy of deep and remote brain tumors and impact of its results on treatment strategy

Year: 2019, volume 15 Issue: №2 Pages: 312-317
Heading: neurosurgery Article type: Original article
Authors: Shabunin A.V., Gorozhanin A.V., Vakatov D.V., Shestakov A.A., Chekhonatsky V.A.
Organization: Clinical Hospital n. a. S. P. Botkin

Purpose: to assess the possibilities of frameless biopsy of brain tumors with deep and hard-to-reach localization and its impact on the treatment strategy. Material and Methods. 56 patients with supratentorial brain tumors of deep and hard-to-reach localization who underwent biopsy using frameless neuronavigation according to accepted standards. Results. In 9 (16.1 %) cases there was a discrepancy between the data of the preliminary MRI examination and the histological conclusion of the punctate after the biopsy, which changed the tactics of treatment. Conclusion. Biopsy of brain tumors of deep and hard-to-reach localization allows you to accurately and least invasive to establish the correct diagnosis. Conducting a frameless biopsy with subsequent immunohistochemical verifcation of the biopsy allows planning adequate further treatment, increasing the duration and quality of life of patients with brain tumors of deep and hard-to-reach localization.

Keywords: treatment

1 Nishihara M, Takeda N, Harada T. Diagnostic yield and morbidity by neuronavigation-guided frameless stereotactic biopsy using magnetic resonance imaging and by frame-based computed tomography-guided stereotactic biopsy. Surg Neurol Int 2014; 5 (Suppl 8): S421-S426
2 Holyavin AI, Nizkovolos VB, Bogdan AA. Quality evaluation of stereotaxis instrument pointing for brain target point using frameless navigation system. Medical Technics 2018; 2 (308): 16–9
3 Barnett GH, Maciunas RJ, Roberts DW. Computer-assisted neurosurgery Taylor & Fracis 2006; 134–41
4 Vakatov DV, Dreval ON, Gorozhanin AV. Properties of supratentorial brain tumor clinical patterns among elderly and senile age patients. Neurosurgery 2006; 3: 25–9
5 White T, Chakraborty Sh, Lall R, Fanous AA. Frameless Stereotactic Insertion of Viewsite Brain Access System with Microscope-Mounted Tracking Device for Resection of Deep Brain Lesions. Technical Report Cureus 2017; 9 (2): 1012–7
6 Orringer DA, Golby A, Jolesz F. Neuronavigation in the surgical management of brain tumors: current and future trends. Expert Rev Med Devices 2012; 9 (5): 491–500
7 Lu Y, Yeung C, Radmanesh A, et al. Comparative Efectiveness of Frame-based, Frameless and Intraoperative MRI Guided Brain Biopsy Techniques. World Neurosurg 2015; 83 (3): 261–8
8 Ekşi MS. A New Era in Stereotactic Brain Biopsy: Frameless Navigation-Based System. J Neurosci Rural Pract 2019; 10 (1): 3
9 Bilger A, Frenzel F, Oehlke O. Local control and overall survival after-frameless radio-surgery: A single center experience. Clin Transl Radiat Oncol 2017; 7: 55–61.

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