Saratov JOURNAL of Medical and Scientific Research

Autonomic dysfunction in patients with chronic cerebral ischemia

Year: 2019, volume 15 Issue: №1 Pages: 167-172
Heading: Neurology Article type: Original article
Authors: Poverennova I.E., Khivintseva E.V., Zakharov A.V., Vasemazova E.N., Ananyeva S.A.
Organization: Samara State Medical University

Various autonomic nervous system (ANS) disorders exist in 25-80% of the general population. Seniors affected by chronic cerebral ischemia (CCI) are subject to the development of autonomic disorders. Purpose: to carry out the analysis of autonomic dysfunction in subjects with CCI. Material and Methods. Autonomic status was evaluated using autonomic function tests. All patients underwent cardiointervalography. Heart rhythm variability was estimated by mode, amplitude, variation range, power of waves of various frequency, coefficient of vagosympathetic balance etc. as measured by "Rhythm-MET" system. One hundred fifty one patients aged 48-93 years were examined and distributed to three groups depending on the degree of severity of CCI. Results were statistically processed using Statistica 6 software. Results. Patients with CCI had differences in autonomic function parameters which had multidirectional character and were dependent on sympathetic-parasympathetic balance and CCI stage. The obtained data demonstrate that prevalence of sympathetic influence was observed in 52.8% patients with I grade CCI, in 64.8% patients with II grade CCI and prevalence of parasympathetic

1 Vejn AM. Vegetative disorders: clinic, treatment, diagnosis. M., 2000; 752 p.
2 Gusev El, Kryzhanovskiy GN. Dysregulation pathology of the nervous system. M., 2009; 512 p.
3 Gonchar IA, Stepanova Yul, Prudyvus IS. Biochemical predictors and markers of cerebral infarction. Minsk: BelMA-PO, 2013; 512 p.
4 Belyavskiy NN. Changes in autonomic regulation in patients with transient ischemic attacks under the influence of interval hypoxic training according to spectral analysis of heart rate variability. Vestnik of Volgograd State Medical University 2008; 7 (3): 1-11
5 Borisov AV, SemakAE. The role of immune and inflammatory factors in the pathogenesis of stroke. Medical news 2010; (1): 3-7
6 Gusev El, KonovalovAN, Skvortsova VI, Geht AB. Chronic insufficiency of cerebral circulation. In: Neurology: National guidelines. M.: GEOTAR-Media, 2009; 1049 p.
7 Kazakov VN, Snegir' MA, Snegir' AG. Ways of interaction of nervous, endocrine and immune systems in the regulation of body functions. Archive of clinical and experimental medicine 2004; 13 (1-2): 3-10
8 Kim SJ, Moon GJ, Bang OY. Biomarkers for Stroke. J of Stroke 2013; 15(1): 26-36
9 Sudakov KV. Theory of functional systems and its application in physiology and medicine. News of biomedical Sciences 2004; (4): 109-33
10 АрапеГ EN. Vojcekhovich GYu, Golovko VA, Mastykin AS. Formalized structural and functional scheme of brain defense mechanisms. In: Fundamental Sciences to Medicine: proceedings of the international conference, 17 May 2013, Minsk. Minsk, 2013; part 1, p. 45-7.

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