Saratov JOURNAL of Medical and Scientific Research

2018, volume 14

Ohtahara II sydrome as a rare epileptic encephalopathy

Year: 2018, volume 14 Issue: №1 Pages: 123-126
Heading: Neurology Article type: Case report
Authors: Akhmadeeva L.R., Vashkevich A.G., Vorontsova L.M.
Organization: Bashkir State Medical University of the Russian Health Care, Ufa "Lege Artis" Clinic
Summary:

We present information about Ohtahara II syndrome which is a rare epileptic encephalopathy, and our own clinical
case: a 4-year old child with this disorder.

Keywords: epileptic encephalopathy, Ohtahara II syndrome

The history of the hospital therapy department of the medical faculty in Saratov state medical university

Year: 2018, volume 14 Issue: №1 Pages: 109-111
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Yudanova L.S., Rebrov А.Р.
Organization: Saratov State Medical University
Summary:

 The article represents the history of the first Department of Therapy at the University founded in September 1911 and describes the stages of its development.

Keywords: Hospital Therapy Department

Professor M.M. Kirillov (to the birth anniversary)

Year: 2018, volume 14 Issue: №1 Pages: 107-108
Heading: anniversary Article type: Short message
Authors: Shapovalova T.G., Ryabova A.Yu., Shashina M.M.
Organization: Saratov State Medical University
Summary:

The article is devoted to the 85th anniversary of the honored doctor of the Russian Federation, Professor M.M. Kirillov.

Keywords: anniversary, M.M. Kirillov

Youth policy at Medical University in conceptual and practical realization

Year: 2018, volume 14 Issue: №1 Pages: 100-106
Heading: Pedagogics and Education Article type: Author's opinion
Authors: Popkov V.M., Bugaeva I.O., Zhivaykina А.А., Loyko V.S., Andriyanova E.A.
Organization: Saratov State Medical University
Summary:

The aim of the article is to consider the main theoretical and practical aspects of implementation the program of youth policy in the Saratov State Medical University n.a. V. I. Razumovsky. Authors analyze the educational system and the way it correlates to modern challenges of the Russian society. Special attention is paid to the main conditions of realization and the directions of youth policy in the Saratov State Medical University. The conceptual principles of youth policy of higher school have been worked out by the authors.

Keywords: educational work, youth policy

The role of museum of Department of Human Anatomy in the educational process

Year: 2018, volume 14 Issue: №1 Pages: 97-100
Heading: Pedagogics and Education Article type: Short message
Authors: Bugaeva O.I., Aleshkina O.Yu., Bikbaeva T.S.
Organization: Saratov State Medical University
Summary:

The article contains information on the history of the formation of the fundamental educational and scientific museum of Human Anatomy department of Saratov State Medical University n.a. V. I. Razumovsky. The main collections of the fund of anatomy museum are presented. Features of registration and registration of anatomical preparations, as well as the purpose of their exposure, are described. The importance of the museum in the educational and scientific process of the department of human anatomy is considered.

Keywords: anatomical preparations, department of human anatomy, museums, Saratov State Medical University n.a. V. I. Razumovsky

A case report of appendicular abscess resulted in hernial sac phlegmon

Year: 2018, volume 14 Issue: №1 Pages: 94-96
Heading: Surgery Article type: Case report
Authors: Shapkin Yu.G., Katalnikov A.E., Starchikhina D.V.
Organization: Saratov City Hospital No6 n.a. V. N. Koshelev, Saratov State Medical University
Summary:

An abnormal clinical case of break of appendicular abscess in incisional ventral hernia complicated phlegmon of
anterior abdominal wall is reported. The observation is of significant importance due to rare frequency of occurrence
in clinical practice, formation of a dangerous complication (phlegmon of anterior abdominal wall), difficult differential
diagnostics (Richter’s strangulatoin bowel or epiploon in hernia with necrosis complicated hernial sac phlegmon or
break of appendicular abscess in incisional ventral hernia). The surgical management was performed followed by a
patient’s recovery.

Keywords: appendicular abscess, incisional ventral hernia, phlegmon of anterior abdominal wall

Acute varicothrombophlebitis: modern approach to the problem

Year: 2018, volume 14 Issue: №1 Pages: 87-94
Heading: Surgery Article type: Review
Authors: Tsarev О.А., Anisimov A.Yu., Prokin F.G., Zakharov A.A., Lobanov A.V., Senin A.A.
Organization: Saratov State Medical University
Summary:

Acute varicothrombophlebitis, or thrombosis of superficial veins (TSV), is a dangerous complication of lower extremity varicose vein disease, as it is a frequent cause for pulmonary artery thromboembolism. The survey states the modern approach to pathogenesis, diagnostics, clinical findings and therapeutic approach to patients with TSV.

Keywords: surgical tactics, undifferentiated dysplasia of connective tissue, varicothrombophlebitis

A comprehensive approach to the diagnosis and treatment of straghorn nephrolithiasis

Year: 2018, volume 14 Issue: №1 Pages: 81-86
Heading: Urology Article type: Review
Authors: Chekhonatskaya M.L., Rossolovsky A.N., Kryuchkov I.A., Bobylev D.A.
Organization: Saratov State Medical University
Summary:

A review of the literature is devoted to the most topical diagnostic questions and treatment of patients with urolithia-sis. The role and the latest advances and benefits of minimally invasive surgery were described. Particular attention was paid to the problems of residual calculi and the condition of the renal parenchyma in the perioperative period. The theme of choice of conducting such patients tactics was considered. The actual diagnostic methods and a differentiated approach to the algorithm choice of the examination and treatment of patients with staghorn nephrolithiasis were considered. The review provided a scientometric analysis of research information (documents reference), contained the analytical array of scientific publications. Electronic information resources of scientific electronic library bibliographic databases: eLibrary, PubMed, Clinical Key, Science Direct — were used.

Keywords: multispiral computed tomography, percutaneous nephrolithotomy, residual stones, urolithiasis

Clinical review of allergic rhinitis in children with parasitic infestation

Year: 2018, volume 14 Issue: №1 Pages: 76-80
Heading: Otolaryngology Article type: Original article
Authors: Nurmukhamedova F.B.
Organization: Tashkent Medical Academy
Summary:

The research goal. Clinical and laboratory data in children with allergic rhinitis (AR) with parasitic infestation (PI) and without it were studied. Material and Methods. The study of AR patients was performed in the children's city diagnostic center. There were 100 children aged 3 to 14 years under our observation. Children were divided on to 2 groups: the main group (67 sick children with permanent allergic rhinitis with concomitant parasitic invasion), and a comparison group (33 patients with permanent allergic rhinitis without parasitic invasion). Results. We found that the clinical picture of AR with concomitant parasitosis in children is characterized by dyspeptic, asthenic vegetative, allergic dermatologi-cal syndromes, in addition to manifestations typical for AR. Conclusion. Analysis of the main clinical and laboratory parameters in children with AR revealed that PI in this case usually occur with subclinical symptoms. In many cases, patients AR required specific parasitological diagnosis allows you to assign a specific therapy is adequate in the detection of concomitant PI.

Keywords: parasitic infestation

Peculiarities of remodeling of hyalin cartilage at early stages of development of degenerative-distrophic processes of knee joints

Year: 2018, volume 14 Issue: №1 Pages: 70-75
Heading: pathological anatomy Article type: Original article
Authors: Gladkova E.V., Romakina N.A., Ananyeva O.E., Belova S.V., Babushkina I.V., Persova E.A., Karyakina E.M.
Organization: Saratov State Medical University
Summary:

The aim is to develop methods for detection of hyaline cartilage metabolic imbalance in patients with initial degenerative dystrophic changes in the substantiated pathogenetically knee. Material and Methods. Subject of inquiry: 50 women aged from 35 up to 57 (49.1 ±2.4), among them 36 patients with an early stage of knee osteoarthrosis made up an experimental group, 14 women without any musculoskeletal disease clinical presentations made up a control group. We carried out a complex examination including physical assessment, study of orthopaedic status, interview with the use of KOOS (Knee Injury and Osteoarthritis Outcome Score) scale, roentgenography and MRI of the knee and also a number of laboratory tests: enzyme-linked immunosorbent assay determination of the content of cytokine profile indices (IL-1, TNF-a, IL-6), cartilage oligomeric matrix protein (COMP) and bone (SerumCrossLaps and bone isozyme of alkaline phosphatase (BAP)) tissue metabolism markers in blood serum in all the groups of patients. Results. In all the patients of the experimental group the roentgenologic stage of osteoarthrosis was defined as 0-1 according to J. Lawrence and J. Kellgren, but at the same time knee degenerative changes were objectivized on the series of MR images in the form of MR signal changes of the articular cartilage, erosions and cysts, degenerative meniscus. We observed increased serum cartilage oligomeric matrix protein (COMP) in the same group and that is characteristic of hyaline cartilage destruction activation. We also detect disorders in bone tissue remodeling in the form of bone resorption intensification (Serum CrossLaps), osteogenesis increase (BAP) and activation of proinflammatory cytokine system link (IL-1, TNF-a). Conclusion. The leading pathogenetic links of the early degenerative changes of the knee are hyperproduction of proinflammatory cytokines (IL-1, TNF-a), destruction of the hyaline cartilage and disorder in bone tissue remodeling. Assessment of biochemical predictors of cartilage and bone tissue degradation along with the instrumental methods of diagnosis is of great theoretical and practical importance in the system of early detection of incipient osteoarthrosis.

Keywords: cartilage oligomeric matrix protein, hyaline cartilage metabolism, incipient gonarthrosis, pathogenesis