Saratov JOURNAL of Medical and Scientific Research

Transfollicular drug delivery: current status of the problem

Year: 2018, volume 14 Issue: №4 Pages: 735-737
Heading: Dermatovenerology Article type: Review
Authors: Talnikova Е.Е., Svenskaya Yu.l., Dobdina A.Yu., Morrison A.V., /UtzS.R./
Organization: Saratov State Medical University

The review is dedicated to one of the promising areas in medicine —transfollicular drug delivery. The article presents
literature data on working principles of this route of administration, main practical aspects and future prospects for its

1 Patzelt A, Lademann J. Drug delivery to hair follicles. Expert Opin Drug Deliv 2013: 10 (6): 787-97
2 HelmstadterA. Endermatic, epidermatic, enepidermatic — the early history of penetration enhancers. Int J Pharm 2011; 416: 12-5
3 Nasir A, Friedman A, Wang S. Nanotechnology in Dermatology. New York/Heidelberg/Dordrecht/London: Springer, 2013; 298 p.
4 Drexler KE. Nanosystems: molecular machinery, manufacturing, and computation. New York: Wiley, 1992; 556 p.
5 Liuzzi R, Carciati A, Guido S. Transport efficiency in transdermal drug delivery: What is the role of fluid microstructure? Colloids and Surfaces B: Biointerfaces 2016; 139 (1): 294-305
6 Gulati N, Gupta H. Parenteral drug delivery: a review. Recent patents on drug delivery & formulation 2011; 5: 133-45
7 Rees JA, Smith I, Watson J. Pharmaceutical Practice. Elsevier Health Sciences, 2014; 570 p.
8 Engelke L, Winter G, Hook S, et al. Recent insights into cutaneous immunization: how to vaccinate via the skin. Vaccine 2015; 33 (37): 4663-74
9 Upadhyay G, Verma S, Parvez N. Recent Trends in Transdermal Drug Delivery System. Advances in Biological Research 2014; 8(3): 131-8
10 Gupta R. Transdermal drug delivery system. World Journal of Pharmacy and Pharmaceutical Sciences 2014; 3: 375-94
11 Manikandan P, Nethaji R, Surenderan N, et al. A review on: Transdermal drug delivery systems. Indo- American Journal of Pharmaceutical Research 2014; 4: 1809-24
12 Singh P, Roberts M. Skin permeability and local tissue concentrations of nonsteroidal anti-inflammatory drugs after topical application. Journal of Pharmacology and Experimental Therapeutics 1994; 268: 144-51
13 Finnin ВС, Morgan TM. Transdermal Penetration. J Pharm Sci 1999; 88 (10): 955-8
14 Allen LV, Popovich NG, Ansel HC. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems. 8th Edition. Lippincott Williams & Wilkins, 2005; 298-315 p.
15 Merkle HP. Transdermal delivery system. Methods Find Exp Clin Pharmacol 1989; 11: 135-53
16 Mahato RA. Pharmaceutical dosage forms&drug delivery. Published by CRS press, 2002; p. 196-7
17 Rosen J, LandriscinaA, Friedman AJ. Nanotechnology-based cosmetics for hair care. Cosmetics 2015; 2: 211-24
18 Antonio JR, Antonio CR, Cardeal ILS, et al. Nanotechnology in dermatology. An Bras Dermatol 2014; 89: 126-36
19 Otberg N, Richter H, Schaefer H, et al. Variations of hair follicle size and distribution in different body sites. J Investig. Dermatol 2004; 122: 14-9
20 Tenjarla SN, Kasina R, Puranajoti P, et al. Synthesis and evaluation of N-acetylprolinate esters-novel skinpenetration enhancers. Int J Pharm 1999; 192: 147-58
21 Toll R, Jacobi U, Richter H. Penetration profile of microspheres in follicular targeting of terminal hair follicles. J Investig Dermatol 2004; 123: 168-76
22 Vogt A, Combadiere B, Hadam S, et al. 40 nm, but not 750 or 1,500 nm, nanoparticles enter epidermal CD1a+cells after transcutaneous application on human skin. J Investig Dermatol 2006; 126: 1316-228
23 Alvarez-Roman R, Naik A, Kalia YN, et al. Skin penetration and distribution of polymeric nanoparticles. J Control Release 2004; 99: 53-62
24 Patzelt A, Richter H, Knorr F, et al. Selective follicular targeting by modification of the particle sizes. J Control Release 2011; 150:45-8
25 Lademann J, Patzelt A, Richter H, et al. Determination of the cuticula thickness of human and porcine hairs and their potential influence on the penetration of nanoparticles into the hair follicles. J Biomed Opt 2009; 14: 1014
26 Schiffer-Korting M, Mehnert W, Korting HC. Lipid nanoparticles for improved topical application of drugs for skin diseases. Adv Drug Deliv Rev 2007; 59: 427-43
27 Wosicka H, Cal K. Targeting to the hair follicles: current status and potential. J Dermatol Sci 2010; 57: 83-98 28 Fang C-L, Aljuffali I A, Li Y-C. Delivery and targeting of nanoparticles into hair follicles. Ther Deliv 2014; 5 (9): 991-1006
29 Chin EY Androgenetic alopecia (male pattern hair loss) in the United States: what treatments should primary care providers recommend? J Am Assoc Nurse Pract 2013; 25: 395-401
30 Mirzoyev SA, Schrum AG, Davis MDP, Torgerson RR. Lifetime incidence risk of alopecia areata estimated at 2.1 %. Delivery & targeting of nanoparticles into hair follicles. J Invest Dermatol 2013:464
31 Nakatsuji T, Kao MC, Fang JY, et al. Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol 2009; 129: 2480-8
32 Iwatsuki K, Yamasaki O, Morizane S, et al. Staphylococcal cutaneous infections: invasion, evasion and aggression. J Dermatol Sci 2006; 42: 203-14
33 Talnikova ЕЕ, Svenskaya Yul, Utz SR, et al. Vitiligo: modern methods of therapy (review). Saratov Journal of Medical Scientific Research 2017; 13 (3): 668-73

2018_4-1_735-737.pdf219.64 KB

No votes yet