Saratov JOURNAL of Medical and Scientific Research
Home

Clinical and morphological features of diagnosis and treatment of various forms of primary hyperparathyorosis

Year: 2017, volume 13 Issue: №3 Pages: 541-543
Heading: Surgery Article type: Original article
Authors: Kovalenko Yu.V., Tolstokorov A.S., Kravchenya A.R., Khubolov A.M., Manakhov G.A.
Organization: Scientific Research Institute of Traumatology Orthopedics and Neurosurgery of Saratov State Medical University n.a. V.I. Razumovsky
Summary:

Objective: optimization of the diagnostic algorithm and treatment methods for different clinical forms of the primary hyperparathyroidism. Material and Methods. The article presents the results of examination and operative treatment of 59 patients diagnosed with the primary hyperparathyroidism, such patients having symptoms specific for the disease or having no symptoms of the same. Results. We have not revealed intraoperative complications after surgical interference; laboratory findings have been normalized in 96.6% of cases. The patients having undergone the surgery have been followed up for 12 months with no relapse. 11.9% of the patients have been diagnosed with the asymptomatic primary hyperparathyroidism. Conclusions. Parathyroidectomy is the only radical and effective treatment for the primary hyperparathyroidism. Parathyroidectomy performed surgically to the proper extent, prevents the relapse as well as development of diseases resulting from the primary hyperparathyroidism.

Keywords: diagnostics, primary hyperparathyroidism , results of surgical treatment

Bibliography:
1. Kalinina АР, Majstrenko NA, Vetshev PS. Surgical endocrinology. St. Petersburg: Piter, 2004; 941 p.
2. Clark ОН, Duh Q, Kebebew Е. Textbook of Endocrine Surgery (2nd ed.). Philadelphia: Elsevier/Saunders, 2005; 674 p.
3. De Groot LJ, Jameson JL. Endocrinology (5th ed.). Philadelphia: Elsevier/Saunders, 2006; 874 p.
4. Cheren'ko SM. Primary hyperparathyroidism: the fundamentals of pathogenesis, diagnosis and surgical treatment. Kiev, 2011; 148 p.
5. Qin L, Raggatt LJ, Partridge NC. Parathyroid hormone: a double-edged sword for bone metabolism. Trends in Endocrinology and Metabolism 2004; 15 (2): 60-65
6. Bilezikian JP, Khan AA, Potts JTJr. On behalf of the Third International Workshop on the Management of Asymptomatic Primary Hyperthyroidism Guidelines for the Management of Asymptomatic Primary Hyperparathyroidism: Summary Statement from the Third International Workshop. The Journal of Clinical Endocrinology & Metabolism 2009; 94 (2): 335-339
7. Wmmer G, Gabriel M, Sieb M, et al. CT-MIBI-SPECT image fusion detects abnormal parathyroid adenomas in patients with goiter: Abstract book of 4th Biennial Congress of European Society of Endocrine Surgeons. Vienna, May 13-15, 2010. 15 p.
8. Rodgers SE, Hunter GJ, Hamberg LM, et al. Improved preoperative planning for directed parathyroidectomy with 4-dimensional computed tomography. Surgery 2006; 140: 932-941
9. Ros S, Sitges-Serra A, Pereira JA, et al. Adenomas paratiroideos de localizacion in tratiroidea: derechosybajos (Intrathyroid parathyroid adenomas: right and lower). Cirugia Espanola 2008: 84 (4): 196-200
10. Bilezikian JP, Silverberg SJ. Clinical practice: Asymptomatic primary hyperparathyroidism. N Engl J Med 2004; 350(17): 1746-1751
11. Nilsson IL, Aberg J, Rastad J, Lind L. Maintained normalization of cardiovascular dysfunction 5 years after parathyroidectomy in primary hyperparathyroidism. Surgery 2005; 137 (6): 632-638.

AttachmentSize
2017_03_541-543.pdf276.83 KB
All articles of the authors: Khubolov A.M. , Kovalenko Yu.V., Kravchenya A.R. , Manakhov G.A.

No votes yet