Saratov JOURNAL of Medical and Scientific Research

ОСТ investigation of influence of cement kiln dust and keratoprotectoral medication on the cornea structure.

Year: 2017, volume 13 Issue: №2 Pages: 400-406
Heading: Ophtalmology Article type: Original article
Authors: Kalmykov R.V., Popova D.V., Kamenskikh T.G., Genina E.A., Tuchin V.V., Bashkatov A.N.
Organization: National Research Tomsk State University, Saratov State Medical University, Saratov state university

The research goal: in vitro study of cornea permeability at the action of cement kiln dust and keratoprotectoral medication. Materials and Methods. Experimental studies were carried out with twenty eyes often rabbits. The measurements were performed using ОСТ system OCP930SR 022 (Thorlabs, USA). Results. ОСТ tomography was used to monitor the attenuation coefficient of the cornea in vitro during the permeability of cement kiln dust and keratoprotector Systein Ultra. The permeability coefficients of the cornea for water, cement dust and keratoprotector were measured. A computer model was developed that allowed one to analyze the diffusion of these substances in the eye cornea. Conclusion. It is shown: 1) cement dust falling on the eye cornea caused pronounced dehydration of the tissue (thickness decreasing) and led to the increase in the coefficient of light attenuation, which in the conditions of cement production could affect the deterioration of the eyesight of workers; 2) the application of the keratoprotector on the eye cornea when exposed by cement dust, slowed significantly the dehydration process and did not cause the increase in the light attenuation coefficient, which characterized the stabilization of visual functions in cement production workers. In this case, the keratoprotector itself did not cause dehydration and led to the decrease in the light attenuation coefficient, which could allow it to be used for a long time in the order to protect the organ of vision from the negative effects of cement dust.

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