№3, 2015, volume 11

The aim of the article is to determine the importance of an integrative approach to identify and analyze the phases or stages of the example of chronic sclerotic disease (CSD). The proposed concept of CSD is to use the diagnostic methods before sclerotic period, based on an analysis of indicators of intensity of the functional systems responsible for collagen formation and collagen lysis taking into account the potential of genetically caused features of sclerosis. Thus, special attention is paid to pre-disease stage including the history and molecular genetic studies which predict the nature of the possible diseases and determine the risk of formation of CSD. The proposed methodology and techniques, as well as obtained with their help data define the possibility of risk groups identification, the direction and volume of the survey.

Objective: evaluation of the differences in the level of temperature, sensory and motor blockade during the various techniques of spinal anesthesia. Materials and Methods. Prospectively the randomized study included 70 patients. In the group with conventional spinal anesthesia (n=35) 15mg of bupivacaine injected quickly. In the group with unilateral spinal anesthesia (n=35) 7.5mg of bupivacaine administered slowly, at a rate of 1 ml per minute. We studied the level of temperature and time, sensory and motor blockade. The data are statistically processed. Results. Reduced thermal sensitivity recorded in an average of 48 seconds as a unilateral spinal anesthesia group and the control group. Subarachnoid administration of 7.5 mg of hyperbaric bupivacaine resulted in the development of a complete motor blockade underlying lower extremity in only 16 patients (45.7%). Conclusion. Using lower dosages of bupivacaine for unilateral spinal anesthesia lowers the threshold concentration of the local anesthetic in the subarachnoid space, resulting in slower motor neuron blockade and it is not total in more than 50% of cases.

The aim of the study is comparative assessment of the influence of separated and combined use of pyrimidine and 3-hydroxypyridine derivatives — xymedon and mexidol on the bone marrow hemopoiesis and peripheral blood quantitative indicators in rats with Walker-256 carcinoma at the doxorubicin and paclitaxel chemotherapy. Materials and Methods. Experiments have been carried out on 83 Wistar female rats of weight 150-250 grams. Doxorubicin in a dose of 4mg/kg and paclitaxel in a dose of 6mg/kg were administered intraperitoneally on the 11th day of experiment. Xymedon (100mg/kg) and mexidol (50mg/kg) were administered separately and in combination with each other, starting with the 11th day of experiment for 10 Says. We estimated myelograms and peripheral blood changes on the 14th and 22d day of the experiment. Results. Xymedon normalized differentiation of granulocytopoiesis cells more effectively than mexidol and reduced severity of erythrocytopenia on the 14th day of the experiment. Combination of xymedon and mexidol accelerated granulocytes differentiation more effectively than separated use of these medicines. It was accompanied by more effective increase of neutrophils number in peripheral blood. Despite the increase of poly-chromatophil normocytes number in bone marrow to the 22d day, the erythrocytes number in blood was not differed from one at separated use of these medicines. Conclusion. Myeloprotective effect of xymedon exceeds the effect of mexidol one. The combination of xymedon and mexidol accelerates granulocytes differentiation more effectively than separated use of these medicines.

Aim: to study antimicrobial activity of variants of polymeric compound polyazolidinammonium modified by iodine hydrate-ions (PAAG-M), depending on the polymeric chain length and concentration of the iodine hydrate-ions against standard strains of gram-positive and gram-negative bacteria as well as microscopic fungi. Materials and methods. Minimum inhibitory concentrations of all variants of the polymeric compound for tested microbial strains have been determined by using serial dilution method. Results. High sensitivity of Eschehchia coli 113-13 and Pseudomonas aeruginosa ATCC 27853 was shown to the variants of PAAG-M with molecular weight

Objective: to identify patterns of typology, age and variability of bilateral forearm bones in children, adolescents and young adults. Material and methods. The method of direct linear osteometry determined length (maximum length) and circumference (maximum circumference of the diaphysis) size of the bones of the forearm. Calculated thickness-length index as a percentage of the maximum circumference of the diaphysis to the greatest length of the bone. Results. The age characteristics of greatest length, the greatest circumference of the diaphysis and thickness-length index, as well as communication with the studied parameters of body length. Conclusion. The largest relative increase in the parameters identified in the second childhood and adolescence. Thickness-length index with age decreases slightly from 16,82 to 15.28% in the ulna (9%) and from 20,26 to 19,24% at the radius (5%). A direct close and substantial connection between the length and circumference of the bone and medium-reverse thickness-length index of forearm bones with age and body length.

Objective: to determine the volume and direction of correlations of length of the proximal phalanges of the 2-5th fingers of the hand with osteometric parameters of phalanges of like fingers. Material and Methods. The length of proximal, medium and distal phalanges, as well as the width and height: the bases, body and heads (distal tuberosity) phalanges of fingers of the hand were studied on 150 skeletons of adult men and women hands at the age 21-90 years old. Results. The correlation between the length of proximal phalanges and pulse- high-rise parameters of proximal, medium and distal phalanges of 2-5th fingers of hand was determined. Conclusion. The length of the proximal phalange forms a different strength and direction of the correlation. The lengths of the proximal phalanges have a positive direction of moderate strength with all parameters of middle phalanges and the average degree of correlation with the length of the distal phalanges, the width of its base and the body.

The aim of the article: to assess the dynamics of the population coverage of preventive inspections dentists. Material and methods: analytical, statistical, and direct observation. Results. Increase in the number of patients receiving artificial limbs, for example, in the North Caucasus Federal District (+21.8% from 2008 to 2009) And Far East (-30.1 % over the same period). Given that in the North Caucasus Federal District smallest number of patients received pros-theses, such a growth indicator may be due to the volume of supply in the region, taking into account the needs of the population. The sharp decline in the availability of prosthetic patients Far East against the background of dissonance between sanitized and in need of rehabilitation patients with sufficient personnel potential evidence of regional problems in dental care. Even more interesting is the distribution of the proportion of patients who received free dentures. In the North Caucasus Federal District, along with an increase in the total number of patients who received artificial limbs, sharply reduced the proportion of patients who received them free of charge (-64.9% from 2008 to 2009). In a number
of countries have not produced any free prosthetics. Conclusion. Reduced the number of patients who received pros-theses, especially for free. The most unfavorable situation is observed in the North Caucasus Federal District (-64.9%), mainly due to the Chechen Republic and the Republic of Dagestan, where the figure is zero. The current situation in the field of dental care, requires a differentiated approach and to adequately address problems from a regional perspective.

The aim of the study: formation of a social portrait of specialist with secondary medical education in the regional healthcare. Materials and Methods. Survey included 464 nurses from medical organizations of the Saratov region. Mathematical and statistical processing of the data was carried out using traditional statistical methods using the application package ("Excel-2003", "BIOSTAT"). Results. The basic features of a professional group and problems of professional realization of nurses in the Saratov region were revealed. Conclusion. Identification of the major professional and social characteristics of the personnel allows to substantiate and to implement targeted measures to create conditions of professional realization of specialists with secondary medical education.