№3, 2015, volume 11

A clinical case of the combination of psoriasis and secondary syphilis is presented. The problem of differential diagnostics of the clinical manifestations of syphilis and psoriasis, including the dermatoscopy usage are considered.

A rare clinical case of an infant acropustulosis at a newborn child is presented in the article clinical signs, histology treatment are described.

The study presents a relatively rare case of dermatosis. It is familial benign chronic vesicular fever (Hailey-Hailey disease) in a 58-years old female patient which is inherited as an autosomal dominant mode. The data about etiology, pathogenesis, clinical picture and differential diagnosis were summarized. The main ways of treatment of the disease are described.

A case of cutaneous mastocytosis, relating to the rarely seen dermatoses, is presented in the study. The data of etiology, pathogenesis, clinical picture are generalize.

The article shows the history and the significance of use of wax masks in the process of visual teaching of dermatology and venereology for students of medical universities in Europe and Russia in the XIX-XX centuries.

Objective: to assess clinical efficiency and safety of using long wavelength ultraviolet therapy in children children and adolescents suffering from atopic dermatitis during exacerbation of the dermatosis. Materials and methods. The data about the usage of the far long-wave UV therapy in the treatment of 38 children suffering from atopic dermatitis. The 2nd group of patients (42 patients) received standard therapy with the use of the usual doses and methods of taking medication and did not differ from the first group by age of patients, duration and form of the disease. Results. All observed on the background of therapy was noted positive dynamics of the pathological process in the skin, however, patients of the 1st group were observed earlier (average 5-7 days) than in the 2nd group, resolution of the clinical manifestations of AD, which was confirmed by a significant decrease in SCORAD values (1,9±0,7; p

The article presents pharmacoeconomics is an essential component of health technology assessment and the appraisal of medicines for use by patients. As a comparatively young discipline, its methods continue to evolve. Pharma-coeconomic analyses encompass cost — minimization, cost — utility, cost — benefit, and cost — effectiveness studies, providing essential information critical for optimization of pharmacotherapy, optimal health-care resource allocation and drug development success.

The article presents a review of the literature devoted to physical therapy of microbial eczema. The issues of the influence of various physical factors on the clinical manifestations and course of the given dermatosis are dicussed. The information about the new treatment of patients with microbial eczema is presented, using visible and infrared radiation transmitted through the water filtration.

The problem of effective treatment of psoriatic arthritis has not been solved yet. The search for new therapeutic options is very active in many directions. At the stage of clinical trials are drugs that block interleukin-17-a (secukinumab, ixekizumab, brodalumab), drugs that suppress interleukin-12 and interleukin-23 (ustekinumab). To modern means to ensure psoriatic arthritis include drugs that are inhibitors of small molecules orkinase pathways (apremilast, tofacitinib).

There is an overview of the current literature data, which reflects the key aspects of the etiology and pathogenesis of psoriasis. A genetically determined, multifactorial nature of the dermatosis was displayed. There were summarized numerous domestic and foreign data on immunological (cellular, humoral, mediator, extravasation, angiogenesis) and non-immune mechanisms of genesis of psoriasis.