Molecular mechanisms of rosacea pathogenesis

Bibliography:
1. Potekaev N. N., Jansen Т., Flajg M. Gemangioma i rozacea // Vestn. dermatol. i venerol. 2000. № 2. S. 32-34; 2. Temnikov V. E. Osobennosti immunnogo statusa pri ro-zovyh ugrjah // Immunologija v dermatovenerologii. 1999. S. 86-88; 3. Laser and light therapies for acne rosacea / K. L. Butter-wick [et al.] // J. Drugs Dermatol. 2006. Vol. 5, № 3. pt. 35. P. 9; 4. Skin immune sentinels in health and disease / F. O. Nestle, Di Meglio P., J.Z. Qin, B.J. Nickoloff// Nat. Rev. Immunol. 2009. Pt. 9. P. 679-691; 5. Snicarenko O.V. Vazoaktivnye polipeptidy pri rozacea // Vestn. dermatol. i venerol. 1995. № 9. S. 42-44; 6. Objective and Quantitative Improvement of Rosacea-As-sociated Erythema after IPL Treatment / K.A. Mark, R. M. Spara-cio, A. Voigt [et al.] // Dermatol. Surg. 2003. Vol. 29. P. 600-604; 7. Samcov A. B. Uchebno-issledovatel»skaja laboratorija klinicheskoj dermatogistopatologii na osnove sistem iskusst-vennogo intellekta // Vestn. Ros. voen.-med. akad. 2000. № 1. S. 94-97; 8. Papules of the face / N. Ghariani, M. Kourda, M. Denguczli [et al.] //Ann. Dermatol. Venereol. 2002. Vol. 129, № 10, pt. 1. P. 1181-1182; 9. Yamasaki K., Gallo R.L. The molecular pathology of rosacea / // Journal of Dermatological Science. 2009. Vol. 55. P. 77-81; 10. Prirodnaja ustojchivost» bakterij к faktoram vrozhden-noj immunnoj sistemy, obuslovlennaja bakterial»nymi proteazami / Ju.A. Tjurin, I.G. Mustafin, R.S. Fassahov// Prakticheskaja me-dicina. Kazan». 2010. № 1. S. 7-13; 11. Toll-like receptors / K. Takeda, T. Kaisho, S. Akira // Ann. Rev. Immunol. 2003. № 21. R. 335-376; 12. Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin / K. Yamasaki, J. Schauber, A. Coda [et al.] // FASEB J. 2006. № 20. R. 2068-2080; 13. Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea / K. Yamasaki, D.A. Nardo, A. Bardan [et al.] // Nat. Med. 2007. № 13. P. 975-980; 14. Cathelicidin LL-37 induces the generation of reactive oxygen species and release of human alpha-defensins from neu-trophils / Y Zheng, F. Niyonsaba, H. Ushio [et al.] // Br. J. Dermatol. 2007. №157. P. 1124-1131; 15. Host defense peptide LL-37, in synergy with inflammatory mediator IL-1 beta, augments immune responses by multiple pathways / J. Yu, N. Mookherjee, K. Wee [et al.] // J. Immunol. 2007. №179. P. 7684-7691; 16. IL-17A enhances vitamin D3-induced expression of cathelicidin antimicrobial peptide in human keratinocytes / M. Peric, S. Koglin, S. M. Kim [et al.]//J. Immunol. 2008. № 181. P. 8504-8512; 17. Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens / M.N. Braff, M. Zaiou, J. Fierer [et al.] // Infect. Immun. 2005. № 73. P. 6771-6781; 18. Angiogenesis in cutaneous disease: part II /V Laquer, V Hoang.A. Nguyen, KM. Kelly//J.Am. Acad. Dermatol. 2009. Vol. 61, № 6. P. 945-960; 19. Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism / J. Schauber, R.A. Dorschner, A. B. Coda [et al.] // J. Clin. Invest. 2007. № 117. P. 803-811; 20. Antimicrobial peptides: key components of the innate immune system / M. Pasupuleti, A. Schmidtchen, M. Malmsten // Crit. Rev. Biotechnol. 2011. [Epub ahead of print]; 21. A New Perspective on Rosacea: The Role of Innate Immunity / L.E. Maier, К Yamasaki, R.L. Gallo // US Dermatol. Rev. 2007. P. 19-21; 22. UV-B-triggered induction of vitamin D3 metabolism differentially affects antimicrobial peptide expression in keratinocytes / M. Peric, V Lehmann, G. Vashina [et al.] // J. Allergy. Clin. Immunol. 2010. № 125. P. 746-749; 23. The potential role of microorganisms in the development of rosacea / E. Lazaridou, S. Giannopoulou, S. Fotiadou [et al.] //J. Dtsch. Dermatol. Ges. 2011. № 9. P. 21-25; 24. Chosidow O. Epidemiology of rosacea: updated data // Ann. Dermatol. Venereol. 2011. Vol. 138 (Suppl. 2) P. 124-128; 25. Impact of vitamin D3 on cutaneous immunity and antimicrobial peptide expression /A.S. Antal, Y. Dombrowski, S. Koglin, [et al.] // J. Dermatoendocrinol. 2011. № 3. P. 18-22; 26. Jones D.A. Rosacea, reactive oxygen species, and aze-laic acid // J. Clin. Aesthetic Derm. 2009. Vol. 2, № 1. P. 26-30; 27. Schauber J., Gallo R. L. The vitamin D pathway: a new target for control of the skin»s immune response // Exp. Dermatol. 2008. №17. P. 633-639; 28. Oxidative stress and ferritin expression in the skin of patients with rosacea / VS. Tisma, A. Basta-Juzbasic, M. Ja-ganjac [et al.] // J.Am. Acad. Dermatol. 2009. Vol. 60, № 2. P. 270-276; 29. Smith J.R., Lanier V B. Expression of VEGF and its receptors in rosacea // Br. J. Ophthalmol. 2007. № 91. P. 226-229; 30. Cuevas R., Arrazola J.M. Therapeutic response of rosacea to dobesilate // Eur.J. Med. Res. 2005. Vol. 10, № 10. P. 454-456; 31. Folkman J., Klagsburn M. Angiogenic factors // Science. 1987. Vol. 235. P. 442-447; 32. Lymphangiogenesis and angiogenesis in non-phyma-tous rosacea /A. N. Gomaa, M. Yaar, M.M. Eyada, J. Bhawan // J. Cutan. Pathol. 2007. № 34. P. 748-753; 33. Functional changes induced by chronic UVA irritation to cultured human dermal fibroblasts / E. Naru, T. Suzuki, M. Moriyama [et al.] // Br. J. Dermatol. 2005. Vol. 153 (Suppl. 2). P. 6-12; 34. Myeloid Differentiation Factor 88 Regulates Basal and UV-lnduced Expressions of IL-6 and MMP-1 in Human Epidermal Keratinocytes/Y Lee, S. Kim, M.H. Shin, K.H. Kim [et al.] // J. Invest. Dermatol. 2009. № 129. P. 460-467; 35. A study of the pathogenesis of Rosacea: how angiogenesis and mast cells may participate in a complex multifactorial process / K. Aroni, E. Tsagroni, N. Kavantzas [et al.] //Arch. Dermatol. Res. 2008. Vol. 300, № 3. P. 125-131; 36. Reactive oxygen species in tumor necrosis factor-alpha-activated primary human keratinocytes: implications for psoriasis and inflammatory skin disease / S. N. Young, J.I. Koepke, L. J. Terlecky [et al.] // J. Invest. Dermatol. 2008. № 128. P. 2606-2614; 37Schauber J., Gallo R.L. Expanding the roles of antimicrobial peptides in skin: alarming and arming keratinocytes // J. Invest. Dermatol. 2007. № 127. P. 510-512.