Saratov JOURNAL of Medical and Scientific Research

Optical coherence tomography of the epidermal sulfakrilate surface strippings

Year: 2013, volume 9 Issue: №3 Pages: 525-529
Heading: Dermatovenerology Article type: Original article
Authors: Utz S.R., Zimnyakov D.A., Galkina Е.М., Yuvchenko S.A., Reshetnikova Е.М., Alonova M.V.
Organization: Saratov State Medical University

Method of the epidermal surface biopsy (ESB) with the adhesive compositions is the alter-native to the classic his-tological examination. Materials and Methods. In this study medical adhesive "Sulfacrylate" was used, small portions of which had been spread on an object glass, and then on different skin areas. To study the structural organization of the samples ESB the technique of optical coherence tomography (ОСТ) was used. Results. We obtained the pictures that visualize the structural organization of the different layers of the epidermis in lichen planus, hyperkeratosis, scabies and other skin diseases. Conclusion. This technique allows non-invasive measurement of high-precision structure of different layers of the epidermis, which can be useful both for research and for the practical dermatology.

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