Saratov JOURNAL of Medical and Scientific Research

№3, 2012, volume 8

Actual problems of integrated system of specialists training

Year: 2012, volume 8 Issue: №3 Pages: 871-875
Heading: Pedagogics and Education Article type: Author's opinion
Authors: Sadchikov D.V., Kuligin А.V.
Organization: Saratov State Medical University
Summary:

The present system of education requires reformation. We have to achieve a new level of educational work. An optimal decision is the module education, as the functional system based on professional standard as on a backbone factor. However, the benefits of module education are useful most of all at a post-graduate stage. Therefore, in training of doctors we have to use 3-stage system (under-graduate, graduate and post-graduate stages) with 2-system approach (topographo-anatomic and functional). This methodology complies best to contemporary requirements for high-qualified doctors and creates necessary conditions for continuous professional progress.

Keywords: module-systemic approach, methodological support, backbone factor

Evolution of Professional Training Forms in Medical Institution of Higher Education

Year: 2012, volume 8 Issue: №3 Pages: 868-870
Heading: Pedagogics and Education Article type: Author's opinion
Authors: Lebedeva M.N.
Organization: Saratov State Medical University
Summary:

Training methodology of medical students has been a subject for profound reforms during the recent years. Revolutionary technological progress is one of the reasons for this process; another reason is a constant search for the most efficient educational ideology. The article presents a historical review of medical education systems in Russia and in Europe. Innovational methods of problem-oriented training, involving use of recent electronic and technical achievements significantly differs traditional scheme, described as a «tutor-student» system. The present work focuses particularly on scientific research as a part of medical training, and its role in preparation of modern medical practitioners. It is stated that doctor is a person who combines professional skills and personal qualities. Therefore complex of technocratic and humanitarian aspects in medical education assists in development of successful training system.

Keywords: medical research training, medical education, history of medicine

Pancreatogenic diabetes mellitus: actual problems of pathogenesis and treatment

Year: 2012, volume 8 Issue: №3 Pages: 862-867
Heading: Endocrinology Article type: Review
Authors: Rebrov А.P., Kunitsyna М.А., Kashkina E.I., Arkhangelskaya Е.Е.
Organization: Saratov State Medical University
Summary:

We have presented the review of literature devoted to the problem of pancreatogenic diabetes mellitus. We have found up that prevalence of pancreatogenic diabetes mellitus needs to be adjusted. In analyzed literature the influence of localization of structural changes of pancreatic tissue on risk of diabetes mellitus development is studied insufficiently. In the result of our literature analysis we have detected that treatment of pancreatogenic diabetes mellitus up to date is not unified and is mostly descriptive, what indicates on necessity of further investigations in order to optimize and increase the efficacy of its treatment.

Keywords: clinical features, pancreatogenic diabetes mellitus, pathogenesis, treatment

Comparative assessment of efficacy of different methods of treatment of pancreatogenic diabetes mellitus in alcoholic and biliary forms of chronic pancreatitis

Year: 2012, volume 8 Issue: №3 Pages: 859-862
Heading: Endocrinology Article type: Original article
Authors: Kunitsyna М.А., Kashkina E.I.
Organization: Saratov State Medical University
Summary:

Aim: the study was devoted to the analysis of efficacy of different methods of treatment of pancreatogenic diabetes mellitus (DM) in alcoholic and biliary forms of chronic pancreatitis (CP). Material and methods. We have observed 86 patients with CP and first diagnosed DM. The assessment of carbohydrate metabolism compensation via HbA1 с level was done using analyzer IMX «Abbot» (USA). Results. At the 1st step of DM treatment we recommended the lifestyle modification and usage of creon 30-60.000 units daily. At the 2d step of treatment if necessary we added glyclazide. Conclusion. We have detected that irrespective of duration of alcoholic form of CP in case of subsequent DM development the lifestyle modification together with replacement ferment therapy in 90% of cases were non-effective. In the result of the research it was established, in case of 3 and more relapses per year in alcoholic form of CPthe probability of achievement of target HbA1 с level in complex with lifestyle changes and replacement ferment therapy was twice low, in connection with that fact the indication of oral anti-diabetic agents became necessary.

Keywords: chronic pancreatitis, diabetes, treatment

Genetic aspects of etiology and development of thyroid gland cancer

Year: 2012, volume 8 Issue: №3 Pages: 854-858
Heading: Surgery Article type: Review
Authors: Kovalenko Yu.V., Tolstokorov A.S.
Organization: Saratov State Medical University
Summary:

Recent studies on thyroid gland cancer development and progression have identified new classes of tumor markers, proto-oncogenes, tumor-suppressing genes, cell receptor genes, identified genetic tumor-predisposing polymorphism and some other significantly important segments of genome. The identification has been based mainly on revealing of DNA abnormal consequences, specific for occurrence of thyroid gland cancer and its progression.

Keywords: proto-oncogenes, thyroid gland cancer, tumor markers

Method of prevention of acute pancreatitis after diagnostic and therapeutic endoscopic retrograde cholangiopancreatography

Year: 2012, volume 8 Issue: №3 Pages: 845-849
Heading: Surgery Article type: Original article
Authors: Tolstokorov A.S., Sarkisyan Z.О., Goch Е.М., Volchkov A.S., Skopets S.М., Dergunova S.A., Rakhnayev D.Ya.
Organization: Saratov State Medical University
Summary:

Objective of the study: Prevention of acute pancreatitis after diagnostic and therapeutic endoscopic retrograde cholangiopancreatography (ERCP). Material and Methods. Analysis of the results of diagnostic and therapeutic ERCP, of the patients treated at Saratov Regional clinical hospital f during the period from 2006 to 2010. Results, lincrease in pancreatic amylase levels in blood above 50 U/l till ERCP is a risk factor for development of acute pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP). Conclusion. The above-stated follows to the background of increased pancreatic amylase levels in blood, performance of endoscopic retrograde cholangiopancreatography led to the development of acute pancreatitis.

Keywords: endoscopic papillotomy, choledocholithiasis, acute pancreatitis

Ratio of degree of funnel chest deformity with severity of connective tissue dysplasia in children

Year: 2012, volume 8 Issue: №3 Pages: 842-845
Heading: Surgery Article type: Original article
Authors: Goremykin I.V., Pogosyan K.L., Lukyanenko Е.А.
Organization: Saratov State Medical University
Summary:

Objective: the study is concerned with the analysis of influence of severity and presence of certain phenotypic signs of nonspecific dysplasia of connective tissue (NDCT) on manifestation and rate of progression of funnel chest deformity (FCD) in children. Materials and methods. 98 patients with FCD aged from 4 to 18 years have been examined. The degree of FCD has been estimated by the index of Gizhytskaya (IG). The structure of phenotypic signs of NDCT has been determined according to M. J. Glesby (1989), the severity of the NDCT has been evaluated by L. N. Phomina tables (2000). Results. It is established, that the degree of FCD in children is significantly associated with severity of NDCT. Conclusion. Prognostically unfavourable factor for rapid progression of FCD in children has been determined by the prevalence of skeletal and articular manifestations among phenotypic signs of NDCT against the background of minimal changes of the skin.

Keywords: funnel chest deformity, interrelation, nonspecific dysplasia of connective tissue

Radiological methods for diagnostics of kidney cancer

Year: 2012, volume 8 Issue: №3 Pages: 834-841
Heading: Urology Article type: Review
Authors: Popkov V.M., Nikolsky Yu.E., Chekhonatskaya M.L, Zakharova N.B., Ponukalin A.N., Zuev V.V.
Organization: Saratov State Medical University
Summary:

It is stated that kidney cancer takes one of the leading places in the cancer incidence. Particular attention should be paid to renal cell carcinoma. By means of modern methods of volume visualization it is possible to diagnose small renal tumors, to prognose the process of tumor development and to save organs by surgical intervention.

Keywords: Radiology, renal cell carcinoma

Low-frequency magnetic field effect on solubility of oxalate type human organominerals in water in vitro

Year: 2012, volume 8 Issue: №3 Pages: 831-834
Heading: Urology Article type: Original article
Authors: PopkovV.M., Usanov D.A., Usanov A. D., Rebrov V.G., Verkhov D.G., Bulanov V.M.
Organization: Saratov state university, Saratov State Medical University, Saratov Laboratory of Forensic Examination
Summary:

The research goal is to determine low-frequency AMF effect on dissolution of urinary stone material in vitro in water with human urinary stones (oxalate type). Materials and Methods. The structural changes in aqueous solutions may occur when exposed to low-frequency alternating magnetic fields (AMF). It depends on chemical composition of the solutions under the study. Results. Organic components (63.1 %), leading to the density decrease of the solution, urea (18.8%), leading to its increase, and oxalic acid (19.7%) have been determined in stone composition. The decrease of transmittance T (%) by the time of oxalate dissolution has indicated increase in concentration of dissolved sample. The sample has been exposed to AMF of 2-9 Hz on the background of the control sample. The growth of this dependence with AMF increasing of 11-22 Hz has established less concentration of dissolved sample in the test solution than in the control one. Conclusion. The main task has been to determine the influence of AMF of 2-22 Hz on solubility of urinary stones placed in water for an hour. The article is to conclude that maximal solubility of oxalate mineral sample by AMF of 2-22 Hz has been reached. It is 14% more than in the control solution. The effectiveness of AMF influence on solubility of organomineral decreases with frequency increasing. It has been confirmed by photometric and areometric measurements.

Keywords: urea, transmittance, solubility of organominerals, density, alternating magnetic field

Коррекция трофологической недостаточности у больных с синдромом компрессионной миелопатии различной этиологии на уровне верхнешейного отдела позвоночника

Year: 2012, volume 8 Issue: №3 Pages: 825-830
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Bajanov S.P., Uljanov V.Yu., Ostrovsky V.V., Shchukovsky V.V., Makarkina E.V., Uljanova E.V.
Organization:
Summary:

Objective: To improve the treatment results of patients with traumatic injuries, and neoplastic lesions of the upper cervical spine on the basis of a differentiated algorithm of nutritional-metabolic therapy. Materials and methods: Based on clinical and instrumental methods of examination typical metabolic characteristics have been studied in 21 patients with compressive myelopathy at the level of the upper cervical spine. Results: Due to the received data differentiated algorithm of nutritional-metabolic therapy has been worked out. Conclusion: The use of nutritional-metabolic therapy in patients with compressive myelopathy at the level of the upper cervical spine may improve the treatment.

Keywords: trophologic insufficiency, treatment, compression myelopathy