Saratov JOURNAL of Medical and Scientific Research

№2, 2012, volume 8

Facilities of different methods of automatic recognition of sleep stages

Year: 2012, volume 8 Issue: №2 Pages: 374-379
Heading: Neurology Article type: Original article
Authors: Antipov O.I., Zakharov A.V., Poverennova I.E., Neganov V.A., Erofeev A.E.
Organization: Samara State Medical University, Samara Regional Clinical Hospital n.a.M. I. Kalinin, Povolzhskiy State University of Telecommunication and Information Technology
Summary:

The gole of the research is to consider the information content in application of different fractal methods of deterministic chaos to the automated recognition of sleep phases in computer electroencephalogram (EEG). The Hurst normalized range method, the method of calculating of Grassberger — Procaccia correlation integral and the approximated entropy method are used during the research. The research reveals that a hypnogram can be obtained. It’s possible if appropriate parameters of the methods indicated above are used, as well as the necessary normalization of the original data and averaging the results. A hypnogram has a total coincidence of defned sleep phases for half of the epochs which are recorded on EEG. Current methods of automatic recognition of sleep stages based on the deterministic chaos allow to reduce signifcantly the time of interpretation of polysomnographic recording and reduce the number of channels through which parameters of sleep are registrated.

Keywords: polysomnography, determined chaos

Chronic pain syndrome at tunnel neuropathies of peripheral nerves. integrative approaches to therapy

Year: 2012, volume 8 Issue: №2 Pages: 371-374
Heading: Neurology Article type: Original article
Authors: Andreyeva G. O., Yemelyanov A. Y.
Organization: Military Medical Academy n.a. S. M. Kirov
Summary:

Painful chronic tunnel syndrome is almost always connected with asthenia and a various degree of anxiety and depressive syndrome. The goal of the research is to investigate prevalence and expressiveness of depressive and astheniс disorders in patients with chronic tunnel pain syndrome and to fnd accommodation of choice. 54 patients with chronic painful tunnel syndrome (35 (64,8 %) male, 19 (35,2 %) female, mean age 39,7+10,9 years) have been examined and treated. Different acupuncture methods in complex treatment were accompanied by a positive dynamics of both subjective and objective clinical neurological and psychological symptoms. Anxiety have been revealed in 79,6 % of patients, depressive syndrome — in 57,3 % of patients, asthenia — in 85,2 % of patients. Acupuncture is tolerable, compare and have not got backside effects. Inclusion of acupuncture in complex treatment chronic tunnel pain syndrome allows to reduce a pain syndrome and asthenia, to normalize psychological condition of the patient.

Keywords: acupuncture, depression, treatment, tunnel syndrome

Clinical and dopplerographic characteristics of headache at men and women with discirculatory encephalopathy

Year: 2012, volume 8 Issue: №2 Pages: 368-371
Heading: Neurology Article type: Original article
Authors: Abramenko U.V., Yakovlev N.A., Slyusar T.A.
Organization: Tver State Medical University of the Ministry of Russia
Summary:

The goal of the research was the comparative analysis of headache clinical implications and ultrasonographic characteristics at women and men with dyscirculatory encephalopathy (DE). 72 women (middle age 64.3) and 48 men with dyscirculatory encephalopathy (DE) of l-ll stage comparable to their age (middle age 65.0) have been examined. The examinations were organized using diagnostic criteria of the International classification of headache disorders (ICDH — II, 2003), headache diary and the McGill Pain Questionnaire. Headache intensity was estimated bythe Visual Analog Scale. Cerebral hemodynamics changes were examined by means of duplex ultrasound of cerebral great vessels and transcranial duplex scanning. The comparative analysis revealed the predomination of tension-type headache among women with DE. They also surpassed men-patients in the indicators of headache intensity, attack duration and frequency. With the help of transcranial duplex scanning (TCDS)was revealed that women with headache were characterized by more severe abnormal venous outflow from the brain. The received data may be important for individualiza-tion of therapeutic approaches at men and women with headache and DE.

Keywords: transcranial duplex scanning, sex, abnormal venous outflow

Kazan period of life-sustaining activity of professor V.I. Ra-zumovsky — a pioneer of Russian neurosurgery

Year: 2012, volume 8 Issue: №2 Pages: 365-368
Heading: Neurology Article type: Review
Authors: Sozinov A.S., Ismagilov M.F., Danilov V.I., Jakupov E.Z.
Organization: Kazan State Medical University
Summary:

There were presented historical data of life-sustaining activity of professor V. I. Razumovsky — a pioneer of Russian neurosurgery, who began to perform and then was performing systematically neurosurgical operations in the Kazan clinic under the guidance of outstanding neurologists V. M. Bekhterev and L. O. Darkshevich.

Keywords: history, neurosurgery, Razumovsky V.I.

Road one hundred years long: history of neurology development in Saratov

Year: 2012, volume 8 Issue: №2 Pages: 357-364
Heading: Neurology Article type: Review
Authors: Popkov V.M., Protopopov A.A., Alenkina E.V., Sholomov 1.1., Voskresenskaya O.N., Kolokolov О.V.
Organization: Saratov State Medical University, First Moscow State Medical University n.a. I.M. Sechenov
Summary:

The article presents information about the history of neurology in Saratov.

Keywords: Tretiakoff K.N., Saratov State Medical University, neurology, Levkovsky A.M.

Contribution of I.I. Molleson to organization and development of sanitary service in Saratov (to the 170-th anniversary of his birth)

Year: 2012, volume 8 Issue: №2 Pages: 341-345
Heading: History of Medicine. Anniversary Dates Article type:
Authors: Zavyalov A.I., Lutsevich I.N., Raikova S.V., Myasnikova I.V.
Organization: Saratov State Medical University
Summary:

The article gives close attention to biography of I.I. Molleson. Consequently, it concerns the scientific and practical contribution of I.I. Molleson to the fight of epidemics, organization and development of sanitary service in Saratov

Keywords: sanitary physician I.I. Molleson, hygiene, biography

The contribution of professor N.S. Efron (dedicated to the 125-th anniversary of his birth) in the development of native dermatology and venerology

Year: 2012, volume 8 Issue: №2 Pages: 339-341
Heading: History of Medicine. Anniversary Dates Article type:
Authors: Utz S.R., Zavyalov A.I., Orkin V.F.
Organization: «Alfa-Centre of Health», Saratov State Medical University
Summary:

The article presents the significant data from biography of N. S. Efron and his scientific contribution to the development of native dermatology and venereology during the period of working at Nicholas Imperial University and Moscow State Institution of Venereology

Keywords: venereology, professor N.S. Efron, dermatology, biography

Functional state of kidneys in patients with clinical manifestations of hypothyroidism

Year: 2012, volume 8 Issue: №2 Pages: 333-338
Heading: Endocrinology Article type: Original article
Authors: Orlova М.М., Rodionova T.I.
Organization: Saratov State Medical University
Summary:

The research goal is to study the function of kidneys and serum concentration of immunoregulatory cytokines (IL-1ГА, IL-6, IL-8, IL-10) in conditions of thyroid hormone deficit. Methods: The character and severity of renal dysfunction were investigated in patients with primary hypothyroidism. The clinical examination included study of serum concentration of creatinine, urea level, potassium and natrium in blood serum, blood and urine analyses, total cholesterol, high and low density lipoproteins, daily microalbuminuria, the performing of Zimnitsky test, urinary excretion of chemokines MCP-1, RANTES, rate calculation of glomerular filtration, thyroid hormone state. Results: The renal function in clinical hypothyroidism without concomitant kidney disturbances was characterized by normal parameters of the concentra-tional kidney function, reduction of glomerular filtration rate, increased of serum creatinine, urea excretion level of chemokine MCP-1 and level of cytokines IL-6, IL-8 in patients with autoimmune hypothyroidism were revealed. Conclusion: It was revealed that autoimmune hypothyroidism effected balance disturbance of cytokine-producing activity of Th1 and Th2 type therefore developing autoimmune state and disease progression

Keywords: thyroid hormones, speed of glomerular filtration, renal function

Effect of hyperbilirubunemia on coagulation system of blood in patients with obstructive jaundice

Year: 2012, volume 8 Issue: №2 Pages: 329-332
Heading: Surgery Article type: Original article
Authors: Tolstokorov A.S, Sarkisian Z.O.
Organization: Saratov State Medical University
Summary:

Objective of the study: determination of the degree of influence of bilirubin in the blood during obstructive jaundice, on blood clotting. Methods. A retrospective study of case histories of patients with obstructive jaundice who have been treated at the Regional Hospital of Saratov in the period from 2000 to 2010. Results. The results confirm the assumption that the causes of bleeding in obstructive jaundice is hepatic failure. Conclusion. Absence of bile in the small intestine in obstructive jaundice is not the cause of bleeding. Bile acids are not involved in metabolizing fat-soluble vitamin K1

Keywords: vitamin K1, obstructive jaundice, hepatic failure, endoscopic papillosphincterotomy, choledocholithiasis

Local medicamentous treatment of wound infection in patients with diabetic foot syndrome

Year: 2012, volume 8 Issue: №2 Pages: 325-329
Heading: Surgery Article type: Original article
Authors: Osintsev E.Yu., Melsitov V.A., Bugaeva I.O.
Organization: Saratov State Medical University
Summary:

The aim of the study was to evaluate the parameters and comparison of wound healing in patients with diabetic foot syndrome using modern dressings and traditional scheme of local treatment of chronic wounds. Materials and methods: Clinical part of the work has been based on the results of a comprehensive investigation of the parameters of wound healing in 154 diabetic foot patients. Results: Optimum results are obtained by treatment of wound infection in patients with neuropathic diabetic foot shape using highly technological dressings. Conclusion: The modern interactive dressings may actively interfere to all phases of wound healing in patients with purulent-necrotic complications of diabetes mellitus

Keywords: wound infection, diabetic foot syndrome, diabetes mellitus type 1