Saratov JOURNAL of Medical and Scientific Research

Characteristics study of cardiac neuropathy formation in patients with metabolic syndrome and carbohydrate metabolism disturbance (according to cardiac rhythm variability analysis data)

Year: 2011, volume 7 Issue: №1 Pages: 079-083
Heading: Internal Diseases Article type: Original article
Authors: Minakov E.V., Kudaeva L.A.
Organization: Voronezh State Medical Academy, Railway Clinical Hospital ad st. Voronezh-1

The research goal is to study the aspects of cardiac neuropathy (CN) of early formation in patients with metabolic syndrome (MS) and carbohydrate metabolism malfunction according to the data of cardiac rhythm variability analysis (CRV). Vegetative status assessment in patients with MS and glucose tolerance disturbance (GTD), MS and type 2 diabetes mellitus (DM-2) has been done relying on the investigation of CRV analysis conventional features, such as RMSSD, pNN50, new approach application based on the determination of rhythmogram short period variations (RSPV), and average rhythmogram variations (RWMV). RSPV monotony raise failure has been revealed by decrease of heart contraction rate in patients with MS and GTD, MS and DM-2. Considerable decrease of RWMV has been observed in patients with MS and DM-2. RWMV values determined within 24 hours have been diminished in the morning in patients with MS and DM-2 and normal at night. RMSSD and pNN50 features have appeared to be significantly diminished in patients with MS and DM-2, they ranging within the normal readings in patients with MS and GTD, though in the morning pNN50 values have been found at the lower tolerance. Primary and completely reversible manifestations of CN have been revealed in patients with MS and GTD; new RWMV feature has been noted to have advantages over the conventional characteristics when diagnosing the signs of CN in patients with MS and GTD

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