Saratov JOURNAL of Medical and Scientific Research

2010, volume 6

Optimization of preparation methods for colon endoscopic investigation

Year: 2010, volume 6 Issue: №4 Pages: 790-793
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: Urjadov S.E.
Organization: Saratov Clinical Hospital N 8
Summary:

The article provides a comparative analysis of the clinical efficacy of intestinal lavage in the preparation of colon to colonoscopy. Sparing regimens and regimens with minimal side-effects were defined. It provides a full endoscopic research, including the case of durable chronic constipation

Keywords: intestinal lavage, fibrocolonoscopy

Value MCP-1 as predict vascular disturbances

Year: 2010, volume 6 Issue: №4 Pages: 786-790
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: Nikitina V.V., Zaharova N.B.
Organization: Saratov State Medical University
Summary:

Vascular disturbances have been studying for more than 150 years. Nowadays vascular disorders cause many diseases. The article presents the significance of monocytic chemotactic protein-1 (MCP-1) and its function in athero-genesis. The data of the research are considered

Keywords: vascular disturbances, monocytic chemotactic protein-1 (MCP-1)

Hemopoiesis indices in patients with diabetes type II with and without vascular complications

Year: 2010, volume 6 Issue: №4 Pages: 783-786
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: Bondar Т.Р., Anfinogenova O.I., Bondar M.V., Soldatov А.А.
Organization: Stavropol State Medical University
Summary:

The article presents data of 1470 case histories and laboratory findings of 290 patients with diabetes and 82 donors who have done such procedure for the first time. Changes of morphological and biophysical indices of erythrocytes, thrombocytes and leukocytes are determined. The analysis of laboratory findings among patients with diabetes complicated by vascular disorders, with diabetes without complications and healthy representatives of the investigation has been carried out. It has revealed significant changes in indices

Keywords: vascular complications, thrombocytes, morphofunctional blood cells state, leukocytes, erythrocytes, diabetes

Etiological structure of bacterial meningitis in children

Year: 2010, volume 6 Issue: №4 Pages: 780-782
Heading: Infectious Diseases Article type: Original article
Authors: K.A. Jafarova
Organization: Azerbaijan Medical University
Summary:

The microbiological investigation of 14 year old children with meningeal and infectious syndromes was held. Bacterial meningitis was diagnosed in 90,9% patients. The meningococcal meningitis was diagnosed in 18 (30%) patients, H. influenzae meningitis - in 9 (15%), S. pneumoniae - in 8 (13,3%). Meningitis as a monoinfection was revealed in 85% cases; mixed infection - in 15%. In 28 patients the etiologic agents of disease were gram-negative, in 16 children -gram-positive bacteria. Causative agents of bacterial meningitis were more resistant to penicillin, ampicillin and eritromycin

Keywords: causative agents, bacterial meningitis

Efficacy of complex treatment of glaucoma optical neuropathy by Cortexin

Year: 2010, volume 6 Issue: №4 Pages: 775-779
Heading: Ophtalmology Article type: Original article
Authors: Shcherbinina I.V., Kamenskikh T.G., Kolbenev I.O.
Organization: Saratov State Medical University
Summary:

The comparative analysis of efficacy of intranasal and intramuscular application of cortexin in combination with transcranial magnetotherapy in patients with primary open-angle glaucoma was conducted. 102 patients (182 eyes) took part in research with primary open-angle glaucoma of I, II, III stages. The most considerable improvement of visual functions resulted from intramuscular and endonasal introductions of cortexin in combination with transcranial magnetotherapy; and longer stabilization of functional indicators was marked in this group

Keywords: transcranial magnetotherapy, neuroprotection, "Cortexin"

Leading factors of cerebral ischemia in newborns

Year: 2010, volume 6 Issue: №4 Pages: 772-774
Heading: Obstetrics and Gynecology Article type: Original article
Authors: Yakovleva O.V., Muzurova L.V., Zryachkin N.I.
Organization: Saratov State Medical University
Summary:

The research goal is to study the causes of perinatal hypoxic impairments of Central Nervous System (CNS) in fetus and newborn. Risk factors of cerebral ischemia development in fetus and newborn are likely to be found anemia, chronic adnexitis in mothers, threatened abortions, athletic type of pregnant women, loop of cord during the pregnancy course, rapid parturition and acute respiratory diseases during the II and III trimesters of pregnancy

Keywords: newborn, fetus, cerebral ischemia

Influence of chronic stress and terahertz radiation at nitric oxide frequency on functional activity of thyroid gland

Year: 2010, volume 6 Issue: №4 Pages: 767-771
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Tsymbal А.А., Kirichuk V.F., Kurtukova М.О.
Organization: Saratov State Medical University
Summary:

In the chronic stress conditions oppression of functional activity of thyroid gland is revealed. Influence of terahertz radiation at the nitric oxide frequency of 150,176-150,664 GHz on functional activity of thyroid gland in the conditions of chronic experimental stress was studied. It was shown that during 15 minutes of influence of terahertz waves at nitric oxide frequency partial restoration of studied indicators of activity of thyroid gland was observed in stressed animals. At 30 minute mode of influence of specified waves a complete recovery of broken indicators of functional condition of thyroid gland was determined

Keywords: thyroid, terahertz radiation, nitric oxide, chronic stress

Heterogeneous peroral medicinal forms in treatment of digestive disorders

Year: 2010, volume 6 Issue: №4 Pages: 762-766
Heading: Clinical Pharmacology Article type: Original article
Authors: Pantyukhin A.V.
Organization: Saratov State Medical University
Summary:

Medicinal form with all its components: auxiliary substances, way of introduction of medicinal substances, favourable properties, appearance and convenience of application influences its therapeutic efficiency. Biological availability of heterogeneous medicinal forms for peroral applications in the form of suspension and emulsion were compared in the research. There were included natural auxiliary substances. Comparative investigations were held on models of experimental gastric ulcer on Okabe and single introduction of hormones. The presented research stated that medical products as components of heterogeneous, correct medicines in the form of suspensions and emulsions positively influence the therapeutic efficiency. Besides, the substances stabilizing heterogeneous systems intensify and supplement pharmacological action of medical product

Keywords: vinylin, lecithin, chitosan, antiacid suspension

Estimates of total costs for treatment of chronic id-iopathic urticaria in adults, depending on the scheme antiallergic therapy

Year: 2010, volume 6 Issue: №4 Pages: 759-762
Heading: Clinical Pharmacology Article type: Original article
Authors: Petrov V.I., Razvalyaeva A.V., Malyuzhinskaya N.V., Gorbunov V.A.
Organization: Volgograd State Medical University
Summary:

Objective: Comparative economic evaluation of clinical application of various alternatives to anti-allergic therapy. The total budget for the treatment of severe chronic idiopathic urticaria for the 12 weeks of the study (4 weeks of therapy and 8 weeks of observation) was assessed according to treatment: Group 1 -cyclosporine2.5 mg/kg/day, Group 2-cetirizine 20 mg and ranitidine 300 mg/day, Group 3 - cetirizine 20 mg. These groups were evaluated by direct medical, direct nonmedical and indirect costs. It was found that the lowest overall cost of treating 100 patients with severe CIU, within 12 weeks of the study were recorded in the group, where a combined therapy of cetirizine 10 mg ranitidine 300 mg. The greatest costs were associated with the appointment of therapy cetirizine 20 mg

Keywords: ranitidine, pharmacoeconomics, cyclosporine, chronic idiopathic urticaria, cetirizine

Состояние медицинского обслуживания пожилого населения и ветеранов в Саратовской области

Year: 2010, volume 6 Issue: №4 Pages: 755-758
Heading: Health Service Organization Article type: Original article
Authors: Novokreshchenova I.G., Senchenko I.K., Michailin V.U.
Organization: Saratov State Medical University
Summary:

На основе изучения данных медико-статистической отчетности выявлено современное состояние проблемы медицинского обслуживания пожилого населения и ветеранов в Саратовской области. Установлено, что в целях наиболее полного удовлетворения особых медико-социальных потребностей пожилого населения и других льготных категорий граждан необходима оптимизация системы медицинского обслуживания на основе обеспечения преемственности деятельности ЛПУ различного статуса, развития внебольничных технологий помощи и учета условий регионального здравоохранения

Keywords: regional healthcare, organization of medical service for elderly and veterans, hospital for war veterans, geriatric aid, daily in-patient forms of medical sevice