Saratov JOURNAL of Medical and Scientific Research

Use glucose tolerance and galactose tolerance tests in dynamics of acute experimental injury of the liver

Year: 2010, volume 6 Issue: №2 Pages: 309-313
Heading: Anaesthesiology and Reanimatology Article type: Original article
Authors: J.V. Tishkova, O.V. Molotkov
Organization: Smolensk State Medical Academy

At adult rats are caused experimental toxic liver injury of the various severity by introduction of carbon tetrachloride in a doze of 0.25 ml and 0.5 ml on 100 g of weights. It is investigated the functional condition of the liver with use glucose tolerance test (GTT) and galactose tolerance test (СаlТТ). It is revealed, the most informative for the investigation of liver function was the end of the first hour from beginning GPr and GаlТТ. Use of the coefficient, reflecting a correlation of glucose concentration in blood at the end of the first hour of ГТТ and Га!ТТ, makes it possible to raise diagnostic value of tolerance tests

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