Saratov JOURNAL of Medical and Scientific Research

Coorection Of Lipid Peroxydation And Antioxydant Protective System By Mexidol And Glycine In Patients With Acute Ethanol Intoxication

Year: 2009, volume 5 Issue: №4 Pages: 507-510
Heading: Clinical Pharmacology Article type: Original article
Authors: A.I. Savlukov, R. N. Kildebekova, R.S. Farshatov
Organization: Ministry of Defense of the RF, Bashkir Military Hospital, Bashkir State Medical University of the Russian Health Care

The research goal is to study lipid peroxydation and ferments of antioxidant protection in group of patients with an acute alcohol intoxication and their correction by medicaments with antioxidant activity (mexidol, glycine and their combination). Patients with diagnosis of ethanol toxic action of moderate severity degree were under study. There were 4 groups - receiving standard therapy, standard therapy and glycine, standard therapy and mexidol, patients receiving standard therapy with combination of mexidol and glycine. Clinical condition and changes in system "lipid peroxidation - antioxidant protection» were estimated. The expressed improvement was revealed applying standard therapy with combination of mexidol and glycine

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